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Vitamin K2 (MK-4)

Vitamin Unit: µg

A form of vitamin K2 found in animal products (meat, eggs, dairy). Supports bone and cardiovascular health.

No established daily requirement for this nutrient.

Top Foods Highest in Vitamin K2 (MK-4)

Amount per 100g serving. Values in µg per 100g.

Foods Highest in Vitamin K2 (MK-4) (Table)

#FoodPer 100gGroup
1Shortening, vegetable, household, composite165 µgFats and Oils
2Margarine, 80% fat, stick, includes regular and hydrogenated104 µgFats and Oils
3Margarine-like, margarine-butter blend, soybean oil and butt72.3 µgFats and Oils
4Snacks, popcorn, microwave, regular (butter) flavor, made wi70.0 µgSnacks
5Cream substitute, powdered68.2 µgDairy and Egg Products
6Crackers, cheese, sandwich-type with cheese filling64.3 µgBaked Products
7Pie Crust, Cookie-type, Chocolate, Ready Crust64.1 µgBaked Products
8KFC, Popcorn Chicken62.3 µgFast Foods
9Pie crust, deep dish, frozen, baked, made with enriched flou61.4 µgBaked Products
10BURGER KING, french fries58.4 µgFast Foods
11TACO BELL, Nachos56.4 µgFast Foods
12Margarine, regular, 80% fat, composite, tub, with salt53.6 µgFats and Oils
13Margarine, regular, 80% fat, composite, tub, with salt, with53.6 µgFats and Oils
14Pie crust, deep dish, frozen, unbaked, made with enriched fl51.7 µgBaked Products
15McDONALD'S, french fries48.6 µgFast Foods
16Snacks, tortilla chips, unsalted, white corn43.7 µgSnacks
17Snacks, tortilla chips, plain, white corn, salted43.7 µgSnacks
18Fast foods, potato, french fried in vegetable oil42.8 µgFast Foods
19Crackers, standard snack-type, sandwich, with peanut butter 42.8 µgBaked Products
20Waffles, plain, frozen, ready -to-heat, toasted35.5 µgBaked Products

Health Effects of Vitamin K2 (MK-4)

Function

Vitamin K2 (MK-4) activates matrix Gla protein (preventing arterial calcification) and osteocalcin (binding calcium to bone). MK-4 is the most prevalent K2 form in animal tissues.

Deficiency Signs

Subclinical K2 insufficiency may contribute to both arterial calcification and reduced bone density. K2 deficiency is harder to detect than K1 deficiency.

Excess / Toxicity

No adverse effects reported from high K2 intake. No UL established specifically for K2 forms.

Absorption & Interactions

How It’s Absorbed

K2 forms are more lipophilic than K1, leading to longer circulating half-life and better tissue distribution. MK-4 has a short half-life (~6-8 hours); longer-chain MK-7 has a much longer half-life (~72 hours).

Key Interactions
Vitamin D Enhancer
D and K2 are highly synergistic: vitamin D upregulates K2-dependent proteins (osteocalcin, MGP), but these proteins only function when activated by K2
Calcium Enhancer
K2 directs calcium to bones and prevents soft tissue calcification; some researchers call K2 the 'calcium traffic director'

Frequently Asked Questions

How much Vitamin K2 (MK-4) do I need per day?

There is no established daily requirement for Vitamin K2 (MK-4).

Which food has the most Vitamin K2 (MK-4)?

The food highest in Vitamin K2 (MK-4) is Shortening, vegetable, household, composite with 165 µg per 100g.

What does Vitamin K2 (MK-4) do in the body?

A form of vitamin K2 found in animal products (meat, eggs, dairy). Supports bone and cardiovascular health.