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EPA (Omega-3)

Fatty Acid Unit: g

Long-chain omega-3 fatty acid important for heart health and reducing inflammation. Found primarily in fatty fish.

No established daily requirement for this nutrient.

Top Foods Highest in EPA (Omega-3)

Amount per 100g serving. Values in g per 100g.

Foods Highest in EPA (Omega-3) (Table)

#FoodPer 100gGroup
1Fish oil, menhaden13.2 gFats and Oils
2Fish oil, salmon13.0 gFats and Oils
3Fish oil, sardine10.1 gFats and Oils
4Oil, bearded seal (Oogruk) (Alaska Native)9.7 gAmerican Indian/Alaska Native Foods
5Fish oil, cod liver6.9 gFats and Oils
6Fish oil, herring6.3 gFats and Oils
7Oil, spotted seal (Alaska Native)3.9 gAmerican Indian/Alaska Native Foods
8Oil, beluga, whale (Alaska Native)2.8 gAmerican Indian/Alaska Native Foods
9Fish, caviar, black and red, granular2.7 gFinfish and Shellfish Products
10Seaweed, agar, dried1.8 gVegetables and Vegetable Products
11Seaweed, spirulina, dried1.8 gVegetables and Vegetable Products
12Fish, mackerel, salted1.6 gFinfish and Shellfish Products
13Fish, roe, mixed species, cooked, dry heat1.3 gFinfish and Shellfish Products
14Fish, herring, Pacific, cooked, dry heat1.2 gFinfish and Shellfish Products
15Fish, salmon, chinook, cooked, dry heat1.0 gFinfish and Shellfish Products
16Fish, roe, mixed species, raw0.98 gFinfish and Shellfish Products
17Fish, herring, Atlantic, kippered0.97 gFinfish and Shellfish Products
18Smelt, dried (Alaska Native)0.91 gAmerican Indian/Alaska Native Foods
19Fish, herring, Atlantic, cooked, dry heat0.91 gFinfish and Shellfish Products
20Salmon, red (sockeye), filets with skin, smoked (Alaska Nati0.91 gAmerican Indian/Alaska Native Foods

Health Effects of EPA (Omega-3)

Function

EPA (eicosapentaenoic acid) is a long-chain omega-3 fatty acid with potent anti-inflammatory properties. It is the precursor to anti-inflammatory eicosanoids (prostaglandins, thromboxanes, leukotrienes) that compete with pro-inflammatory omega-6 derivatives.

Deficiency Signs

EPA insufficiency is associated with chronic inflammation, increased cardiovascular risk, and mental health disorders (depression, anxiety). Most Western diets are low in EPA.

Excess / Toxicity

Very high doses (>3g/day combined EPA+DHA from supplements) may increase bleeding time. Fish oil supplements can cause GI side effects at high doses.

Absorption & Interactions

How It’s Absorbed

Readily absorbed in the small intestine from triglyceride form (fish) or ethyl ester form (supplements). Absorption is enhanced when taken with a fat-containing meal.

Key Interactions
DHA (Omega-3) Enhancer
EPA and DHA work together; EPA provides anti-inflammatory eicosanoids while DHA supports membrane structure
Linoleic Acid (Omega-6) Inhibitor
EPA-derived eicosanoids compete with omega-6-derived pro-inflammatory eicosanoids; the ratio of omega-6:omega-3 influences inflammatory balance

Frequently Asked Questions

How much EPA (Omega-3) do I need per day?

There is no established daily requirement for EPA (Omega-3).

Which food has the most EPA (Omega-3)?

The food highest in EPA (Omega-3) is Fish oil, menhaden with 13.2 g per 100g.

What does EPA (Omega-3) do in the body?

Long-chain omega-3 fatty acid important for heart health and reducing inflammation. Found primarily in fatty fish.