Most people don’t realise the intrinsic relationship between nutrition and sleep, but the reality is that they are inseparable. Each is constantly influencing the other in ways that either support your wellbeing or undermine it.
You might optimise your sleep environment, establish consistent sleep and wake times, build a proper wind-down routine, sort your light exposure, implement stimulant management, and make exercise a regular practice, and you’ve may have done the hard work of building solid sleep hygiene habits overall. But there’s another foundational element that profoundly affects how well you sleep: what you eat, when you eat it, and how much you consume.
The relationship works in both directions. What you eat affects how well you sleep; meal timing, macronutrient composition, specific nutrients, and overall diet quality all influence sleep onset, sleep architecture, and how rested you feel upon waking. And how well you sleep affects what you eat; sleep deprivation increases appetite, intensifies cravings for hyperpalatable foods, impairs impulse control, and makes maintaining healthy eating patterns genuinely more difficult.
This bidirectionality creates feedback loops that either support or undermine both domains. Good nutrition supports good sleep, which makes maintaining good nutrition easier, which improves sleep further. Poor nutrition disrupts sleep, which drives worse food choices, which degrades sleep more. Understanding this relationship allows you to deliberately create the upward spiral rather than being caught in the downward one.
This article will give you a comprehensive understanding of how nutrition affects sleep, from basic principles of adequate calories and balanced macronutrients to specific micronutrients that support sleep, meal timing strategies that optimise sleep quality, foods and substances that help or hinder sleep, and practical implementation that fits real life. We’ll address the nuances, the individual variation, and the honest trade-offs involved when goals conflict.
But as we get stuck into this, it is important to keep in mind that this isn’t about perfection or obsessive optimisation. It’s about understanding which nutritional factors meaningfully affect sleep so you can make informed choices, and which factors are largely irrelevant so you can ignore the noise and focus on what actually matters.
Table of Contents
- 1 The Bidirectional Feedback Loop: Understanding How It Works
- 2 General Nutrition Principles: The Foundation
- 3 Calorie Intake and Sleep: Finding the Balance
- 4 Macronutrients and Sleep: What Actually Matters
- 5 Micronutrients and Sleep: The Nutrients That Matter
- 6 Meal Timing: When You Eat Matters Significantly
- 7 Hydration: The Balancing Act
- 8 Alcohol and Sleep
- 9 Cannabis and Sleep
- 10 Foods and Sleep: What Helps, What Hinders
- 11 Practical Implementation: Making It Work
- 12 Troubleshooting Common Problems
- 13 Nutrition and Sleep Conclusion
- 14 Author
The Bidirectional Feedback Loop: Understanding How It Works
The relationship between nutrition and sleep operates as a feedback loop, and understanding this helps explain why sleep problems and eating problems so often occur together.
Diet affects sleep through multiple pathways: Inadequate calories increase stress hormones and reduce leptin (the satiety hormone), both of which fragment sleep. Imbalanced macronutrients can affect neurotransmitter production, blood sugar stability, and satiety, which are all relevant for sleep quality. Insufficient micronutrients like magnesium, B vitamins, and vitamin D directly impair sleep architecture. Poor meal timing creates digestive discomfort, blood sugar fluctuations, and temperature changes that interfere with sleep onset and maintenance.
Sleep affects diet through equally powerful mechanisms: Sleep deprivation increases ghrelin (the hunger hormone) and decreases leptin, making you genuinely hungrier and less satisfied after eating. It impairs prefrontal cortex function, which affects decision-making and impulse control around food. It increases reward centre activation in response to hyperpalatable foods, so after poor sleep, processed foods become more appealing whilst vegetables become less so. It increases fatigue, which reduces the energy available for meal planning and preparation.
The research on this is quite robust, and people who are sleep-deprived consume 200-300 more calories per day on average, with most of those calories coming from snacks and highly palatable foods rather than balanced meals. They show increased preference for carbohydrates and fats and decreased preference for proteins and vegetables.
Breaking negative cycles: If you’re experiencing both poor diet and poor sleep, each reinforcing the other, you need to intervene on one side to create momentum. Often, addressing sleep hygiene practices first begins improving sleep within weeks, which then makes dietary changes more manageable because you have better self-regulation and energy. Alternatively, if your diet is particularly problematic (severe restriction, extreme imbalance, clear deficiencies), addressing nutrition first might be necessary because it’s directly impairing sleep.
Creating positive cycles: Once you’ve established reasonable competence in both domains and you are sleeping adequately most nights, and eating reasonably well most days, the two begin reinforcing each other positively. Good sleep makes healthy eating easier. Healthy eating supports good sleep. Small improvements in one create small improvements in the other, compounding over time.
General Nutrition Principles: The Foundation
Before discussing sleep-specific strategies, we need to establish the foundational general principles of adequate nutrition that support overall health, which in turn support sleep.
Whole foods foundation: Basing your diet primarily on minimally processed whole foods like vegetables, fruits, whole grains, legumes, nuts, seeds, eggs, fish, meat, and dairy (if tolerated), provides the nutrient density, fibre, and satiety that support metabolic health and sleep quality. Highly processed foods, particularly those high in refined carbohydrates and added sugars, are associated with worse sleep quality independent of calorie intake.
This doesn’t mean never eating processed foods; it just means that the foundation of your diet, and what you eat most consistently, should be whole foods. Occasional processed foods won’t derail your sleep if your baseline is solid.
Appropriate calories: Consuming neither too many nor too few calories for your needs and goals. Both extremes impair sleep, though through different mechanisms we’ll explore shortly.
Adequate protein: Research suggests 1.5-2g of protein per kg of body weight supports sleep quality, satiety, and metabolic health. This typically means 100-180g daily for most adults. Protein should be distributed relatively evenly across meals, with particular attention to ensuring adequate protein at dinner.
Balanced macronutrients: Adequate carbohydrates to support activity and metabolic function (typically 40-50% of calories), sufficient fats for hormone production and nutrient absorption (typically 25-35% of calories), alongside your protein target. Extreme restriction of any macronutrient can impair sleep for some people.
Sufficient micronutrients: Meeting needs for essential vitamins and minerals through varied diet and supplementation when necessary. Multiple micronutrients directly affect sleep, and deficiencies create problems that sleep hygiene alone cannot overcome.
For comprehensive nutrition guidance beyond sleep-specific considerations, you’d need to read our more in depth and dedicated nutrition resources. For our purposes, understand that sleep-specific strategies work best when built on a foundation of generally adequate nutrition.
Calorie Intake and Sleep: Finding the Balance
The amount you eat relative to your needs profoundly affects sleep quality, but the relationship is complex and depends on your current body composition and goals.
Calorie Deficit and Sleep
Calorie restriction for fat loss can impair sleep quality through several mechanisms: hunger creates discomfort that interferes with sleep onset and causes awakenings. Calorie restriction increases cortisol, particularly with larger or prolonged deficits. Low leptin levels (which decline with fat loss) affect the hypothalamus in ways that fragment sleep and reduce deep sleep. The metabolic stress of sustained energy deficit creates heightened arousal that works against the calm needed for sleep.
Magnitude matters: A small deficit (10-20% below maintenance, aiming for 0.5% body weight loss per week) produces minimal sleep disruption for most people. A moderate deficit (20-30% below maintenance, 1% body weight loss per week) causes noticeable sleep problems for many. A large deficit (30-40%+ below maintenance, 1.5-2+ pounds weekly) reliably impairs sleep for nearly everyone. This doesn’t mean it will absolutely tank your sleep, but it will be affected.
Body composition matters: Leaner individuals experience worse sleep disruption during calorie restriction than people with higher body fat levels. Someone at 15% body fat will experience substantially worse sleep impact than someone at 30% body fat with identical deficit sizes, because leptin drops more dramatically at lower body fat levels, and you do just simply have less easily accessible energy stores available to you for sleep processes.
The fundamental trade-off: You’re often choosing between faster fat loss and better sleep. Aggressive deficits produce faster results but worse sleep and reduced adherence. Moderate deficits are slower but sustainable with acceptable sleep quality.
Mitigation strategies when dieting:
- Use the smallest deficit that produces acceptable progress (often 0.5-0.75% body weight loss weekly)
- Include diet breaks where you spend time eating at maintenance for 1-2 weeks every 6-8 weeks allows sleep to normalise temporarily
- Emphasise protein (higher end of recommended range) for satiety and muscle preservation
- Consider strategic carbohydrate timing with more at dinner if this improves sleep
- Prioritise sleep alongside fat loss, and accept that optimising both simultaneously has limits
If sleep is your priority, maintaining weight or using a very small deficit is ideal. If fat loss is your priority, use a moderate deficit and accept some sleep compromise whilst implementing every other sleep optimisation strategy available.
Calorie Surplus and Maintenance
Eating at or above maintenance calories generally supports sleep quality. Adequate energy availability reduces stress hormones, maintains healthy leptin levels, and creates metabolic conditions conducive to good sleep. People in muscle-building phases often report excellent sleep.
However, chronic substantial overeating, particularly large amounts close to bedtime, can impair sleep through digestive discomfort, reflux, elevated blood sugar fluctuations, and increased core temperature from the thermic effect of food.
From a pure sleep perspective, eating at or slightly above maintenance is ideal. Weight stability is associated with better sleep quality than either weight loss or rapid weight gain. This doesn’t mean you shouldn’t pursue body composition goals, but it does mean that you should recognise the trade-offs involved.
Macronutrients and Sleep: What Actually Matters
The balance of protein, carbohydrates, and fats affects sleep quality, though the effects are sometimes more modest than popular nutrition advice suggests, and individual variation is substantial.
Protein
Adequate protein supports sleep through multiple mechanisms: providing tryptophan (a serotonin and melatonin precursor), enhancing satiety (reducing hunger-driven awakenings), and stabilising blood sugar.
Research suggests 1.5-2g of protein per kg of body weight supports sleep quality and overall health. Distribution across the day matters too, with particular emphasis on adequate protein at dinner (25-40g depending on body size) to prevent late-night hunger and support overnight muscle protein synthesis.
If you’re waking up hungry in the middle of the night or early morning, insufficient protein at dinner is a likely contributor.
Carbohydrates
Carbohydrates have gotten an undeserved bad reputation regarding sleep. Moderate carbohydrate intake, including at dinner, generally supports rather than impairs sleep.
Mechanisms supporting sleep: Carbohydrate ingestion triggers insulin release, which facilitates uptake of competing amino acids into muscles. This increases the tryptophan-to-competing-amino-acids ratio in blood, potentially allowing more tryptophan to cross the blood-brain barrier for conversion to serotonin and melatonin. Carbohydrates also help maintain serotonin levels important for mood and sleep regulation. This isn’t necessarily the only mechanism, and it may just be a good “just-so” story, but the fact is that many people do find that eating enough carbohydrates does help with their sleep.
Individual variation is real: Some people genuinely benefit from having substantial carbohydrates at dinner, and they report easier sleep onset and deeper sleep. Others find that large evening carbohydrate intake makes them sleepy initially but causes middle-of-night waking, possibly through blood sugar fluctuations. Still others notice no particular relationship.
This variation likely relates to individual differences in glucose tolerance and insulin sensitivity. As a result, you will need to experiment: try having 40-50% of daily carbohydrates at dinner for a few weeks, then try distributing them more evenly, and notice which produces better sleep for you.
Quality matters: Complex carbohydrates from whole grains, starchy vegetables, legumes, and fruits provide sustained glucose release and micronutrients. Refined carbohydrates and added sugars produce rapid spikes and crashes that can disrupt sleep.
Very low carbohydrate diets: Ketogenic or very low carbohydrate approaches (below 50-100g daily) impair sleep for most people, particularly during adaptation. Mechanisms include reduced serotonin production and elevated cortisol during metabolic adaptation. Some people adapt without sleep issues after several weeks. Others experience persistent sleep problems until carbohydrate intake increases. Unfortunately, a lot of people mistakenly believe that this is actually a benefit of the low carb diet, when in reality it is just a mild stress response keeping them awake.
If you’re following a very low-carbohydrate diet and experiencing sleep problems, increasing to even 100-150g daily often resolves issues while maintaining many metabolic adaptations.
Fats
Dietary fat is essential for hormone production, vitamin absorption, satiety, and overall health. Adequate fat intake supports sleep quality.
Evening fats are fine: Contrary to some claims, consuming moderate fats at dinner as part of a balanced meal doesn’t impair sleep. Fat provides satiety and stabilises blood sugar.
Avoiding excessive amounts: Very large amounts of fat in a single meal can cause gastrointestinal discomfort that interferes with sleep. But moderate fat from nuts, avocados, olive oil, fatty fish, or other whole food sources at dinner is beneficial, not problematic.
Omega-3 fatty acids: Higher omega-3 intake (from fatty fish or supplements) is associated with better sleep quality in some research. The effect isn’t dramatic, but emphasising omega-3-rich foods (fatty fish 2-3 times weekly) is reasonable if optimising nutrition for sleep.
Micronutrients and Sleep: The Nutrients That Matter
Several vitamins and minerals directly affect sleep quality, and deficiencies create sleep problems that no amount of sleep hygiene can fully overcome.
Magnesium
Magnesium might be the single most important mineral for sleep quality. It promotes muscle relaxation, enhances GABA activity (the primary calming neurotransmitter), regulates melatonin production, and affects circadian rhythm.
Deficiency is common: Surveys suggest 40-50% of people in Western countries consume less magnesium than recommended. Soil depletion, food processing, and inadequate vegetable intake all contribute.
Symptoms: Muscle cramps or tension, restless legs, difficulty relaxing, frequent nighttime awakenings, and feeling unrefreshed despite adequate time in bed are all potential symptoms of not enough magnesium.
Food sources: Dark leafy greens, nuts and seeds, whole grains, legumes, dark chocolate, avocados. If your diet includes substantial amounts of these foods, you’re likely getting adequate magnesium. If not, you might be deficient.
Supplementation: Magnesium glycinate is best absorbed and least likely to cause digestive upset. 200-400mg elemental magnesium taken 30-60 minutes before bed is a reasonable starting point. Many people notice improved sleep within a few days, though not everyone responds.
Vitamin D
Vitamin D deficiency is extremely common, particularly in northern latitudes, during winter, and among people who work indoors. Deficiency is associated with poor sleep quality, difficulty falling asleep, shorter sleep duration, and daytime sleepiness.
Deficiency prevalence: Many people in temperate and northern climates are deficient in winter. People who work indoors, use sunscreen consistently, have darker skin, or are elderly are at higher risk.
Testing and supplementation: Unlike nutrients where dietary intake is typically sufficient, vitamin D often requires supplementation because food sources are limited. Testing is straightforward and inexpensive. If deficient, supplementation with vitamin D3 at 2,000-5,000 IU daily typically brings levels into the optimal range over several months.
B Vitamins
Several B vitamins are involved in neurotransmitter synthesis and sleep regulation:
Vitamin B6: Required for converting tryptophan to serotonin and melatonin. Food sources include poultry, fish, potatoes, chickpeas, and bananas.
Vitamin B12: Involved in circadian rhythm regulation. Deficiency is associated with sleep-wake cycle disruption. Food sources are animal products exclusively, so vegans and vegetarians need supplementation. Older adults often have reduced absorption and may need supplementation.
Folate: Works with B12 in neurotransmitter synthesis. Food sources include leafy greens, legumes, some organ meats and fortified grains.
Other Important Micronutrients
Calcium: Works with magnesium and is involved in melatonin production. Most people get adequate amounts from dairy or fortified plant milks.
Iron: Strongly associated with restless legs syndrome when deficient. Women of reproductive age and vegetarians/vegans are at higher risk. Don’t supplement without testing, as excess iron creates problems.
Zinc: Involved in sleep regulation through neurotransmitter function. Food sources include oysters, shellfish, red meat, poultry, legumes, nuts, and seeds.
Meal Timing: When You Eat Matters Significantly
The timing of food intake relative to sleep affects sleep quality through multiple mechanisms: thermic effect of food, digestive demands, blood sugar fluctuations, and core temperature changes.
The 2-3 Hour Pre-Bed Cutoff
For most people, finishing eating at least 2-3 hours before bedtime produces better sleep quality than eating closer to bedtime.
Why late eating disrupts sleep: When you eat, your metabolic rate increases through the thermic effect of food, as your body generates heat to digest and process nutrients. This temperature increase works against the temperature drop needed for sleep initiation. Digestion requires substantial energy and blood flow, creating physiological activity incompatible with deep rest. Lying down with a full stomach increases reflux risk. Large or poorly balanced meals create blood sugar fluctuations that can disrupt sleep.
If your bedtime is 10:30pm, finishing dinner by 8:30pm at the latest (ideally 7:30pm) allows adequate time for digestion before sleep.
Individual variation exists: Some people tolerate later meals better than others. People with faster gastric emptying and better insulin sensitivity might do fine finishing dinner 90 minutes before bed. People with slower digestion or reflux problems might need a full 3 hours. Experiment to find what works, but use 2-3 hours as your starting point.
Exceptions and Special Cases
Small snacks if genuinely needed: If you’re actually hungry before bed, and I don’t mean bored or habituated, but genuinely hungry, a very small snack (100-200 calories) of easily digestible protein and fat (Greek yogurt, small handful of nuts) can provide satiety without the digestive load of a full meal.
The key is distinguishing genuine hunger from habit, boredom, or emotional eating. If you’re eating adequate meals at appropriate times, late-night hunger shouldn’t be common.
Athletes with high calorie needs: People training heavily sometimes need to eat closer to bedtime simply to consume enough calories. In these cases, choose easily digestible foods, avoid excessive fat or fibre in late meals, and allow as much time as practical.
Blood sugar regulation issues: Some people with diabetes or blood sugar regulation problems benefit from a small protein-fat snack before bed to stabilise overnight blood sugar. This requires individual assessment, potentially with medical guidance.
Last Meal Composition
Your dinner should be balanced: adequate protein (25-40g), moderate complex carbohydrates, modest fats, and fibre from vegetables. This creates satiety, stabilises blood sugar, and generally supports good sleep.
Avoid excessive food volume (feeling uncomfortably full), very spicy foods (if they cause discomfort), highly acidic foods (if you’re prone to reflux), and very heavy, greasy meals that digest slowly.
You need to know your personal triggers; if certain foods reliably create digestive discomfort, avoid them at dinner, even if they’re generally healthy.
Hydration: The Balancing Act
Adequate hydration is essential for sleep quality, but excessive hydration before bed creates its own problems through nighttime urination that fragments sleep.
Overall adequate hydration: You should be well-hydrated throughout the day, with urine that’s pale yellow. Dehydration creates discomfort and metabolic disturbances that impair sleep.
Evening taper: Consume most of your daily water earlier, ideally in the morning and afternoon. From 2-3 hours before bed, reduce intake substantially. Drink when genuinely thirsty, but don’t continue constant water consumption right until bedtime.
Individual variation: Bladder capacity varies enormously. Some people can drink normally until bed without issues. Others wake multiple times with any fluid within 3 hours of bed. I know I personally can drink a litre of water right before bed with no issues, but I know others who will be up 2-3 times that night to urinate if they even have a small glass of water.
Age affects this, as do medical conditions and certain medications.
Either way, if you’re waking regularly to urinate and it’s fragmenting your sleep, experiment with earlier cessation of fluid intake.
Alcohol and Sleep
Alcohol might be the single worst commonly consumed substance for sleep quality, and it’s particularly problematic because it feels like it helps initially.
Alcohol is a sedative, and it reduces anxiety and often makes falling asleep easier. This leads many people to use it as a “sleep aid.” But what alcohol actually does to sleep architecture is profoundly negative.
Effects on sleep:
- Dramatically suppresses REM sleep, particularly in the first half of the night
- Increases sleep fragmentation, so you wake more frequently, often without remembering
- Creates dehydration
- Causes rebound insomnia in the second half of the night as alcohol metabolises
- Worsens snoring and sleep apnea
- Disrupts sleep architecture even in small amounts
Even moderate amounts matter: Research shows that even one standard drink consumed in the evening measurably reduces sleep quality. Two drinks produce substantial disruption. Three or more essentially guarantee poor sleep despite potentially falling asleep quickly.
Timing: Alcohol metabolises at roughly 7-10g (half a drink) per hour. Two glasses of wine at 7pm won’t be fully cleared until 9-10pm, and sleep disruption extends beyond blood alcohol levels through effects on neurotransmitter systems.
Recommendation: Ideally, avoid alcohol if sleep is a priority. If you do drink, limit to 1-2 drinks maximum, finish by 6-7pm if sleeping at 10:30pm, and accept that sleep quality will be compromised that night. Don’t use alcohol regularly as a sleep aid, as it creates dependence while destroying sleep architecture.
Cannabis and Sleep
Cannabis is increasingly used for sleep, particularly where legal. Like alcohol, it often helps with sleep onset but negatively affects sleep architecture.
THC suppresses REM sleep, creates rapid tolerance (requiring more for the same effect), and causes withdrawal insomnia when regular users stop. It’s not a long-term solution and often creates the sleep problems people are using it to solve.
CBD without THC appears less problematic and might have anxiolytic effects that help some people sleep, though research is still emerging.
Foods and Sleep: What Helps, What Hinders
Beyond the major factors and components of the diet, specific foods have been studied for their effects on sleep. Effects are generally modest, and you won’t fix serious sleep problems by adding tart cherry juice, but for someone optimising after addressing fundamentals, these are worth considering.
Foods that may impair sleep:
- High sugar foods (blood sugar spikes and crashes, particularly evening consumption)
- Very spicy foods (increased body temperature, GI discomfort for some)
- Very heavy, greasy meals (slow digestion, reflux risk)
- High-acid foods for those prone to reflux (tomatoes, citrus, vinegar)
- Foods you’re personally sensitive to (causing bloating, gas, discomfort)
Foods that may support sleep:
- Tart cherry juice (contains small amounts of melatonin)
- Kiwi fruit (some research shows benefit, but the mechanism unclear)
- Fatty fish (omega-3s and vitamin D)
- Nuts and seeds (magnesium, healthy fats)
- Whole grains (complex carbs, B vitamins)
- Dairy if tolerated (calcium, tryptophan)
- Herbal teas (chamomile, valerian, etc. offer modest effects, and the ritual may matter more)
None are magic solutions, but incorporating supportive foods whilst avoiding problematic ones can provide incremental improvement for someone with solid fundamentals.
Practical Implementation: Making It Work
Understanding principles is one thing. Actually implementing changes whilst managing real-life constraints is another.
Planning Dinner for Sleep
Your dinner should be:
- Balanced: adequate protein (25-40g), moderate complex carbohydrates, modest fats, and vegetables
- Satisfying but not uncomfortably full
- Finished 2-3 hours (or more) before bedtime
- Consistent in timing to support circadian rhythm
- Free from foods that trigger your personal digestive issues
It doesn’t need to be more complicated than that really. Of course, this does need to be against a back drop of adequate total calories too.
Managing Practical Constraints
If you work late: Consider meal prep on weekends (2-3 hours Sunday for 3-4 dinners) or extremely simple weeknight meals (15-minute preparation), so you aren’t spending an hour cooking when you get home, or a maybe try larger lunch with a lighter dinner.
If you have young children: Their dinner timing might work well for you too. Or you might need to eat early with them and skip the later “adult dinner” to maintain proper timing.
If you train in the evening: Consider training earlier when possible, eating before training with post-workout being a lighter meal, or accepting some sleep compromise if evening training is non-negotiable.
The key is recognising which constraints are truly fixed and which are choices you’re making, then working within actual constraints whilst adjusting what you can.
Troubleshooting Common Problems
Waking hungry at night: Eat more at dinner, have dinner slightly later (whilst maintaining 2-hour minimum), include small protein-fat snack before bed if genuinely needed. If persistent despite adequate dinner, consult a healthcare provider about blood sugar regulation.
Heartburn or reflux: Finish eating 3 hours before bed, avoid trigger foods at dinner, don’t lie completely flat (slightly elevate head of bed), eat smaller dinners, see a doctor if severe or persistent.
Always thirsty at night: Increase daytime hydration, investigate medical causes (diabetes causes excessive thirst), reduce dinner salt intake, consider mouth breathing from nasal congestion or sleep apnea.
Dieting and can’t sleep: Reduce deficit size, include diet breaks, ensure adequate protein, consider increasing carbohydrates slightly (particularly at dinner), and accept that some sleep disruption is an inevitable trade-off with aggressive dieting.
Nutrition and Sleep Conclusion
The relationship between nutrition and sleep extends far beyond simple optimisation. How you eat affects your sleep quality, which affects your energy, mood, cognitive function, and capacity to maintain healthy eating patterns. The two create feedback loops that either support or undermine your overall well-being.
You’re not optimising separate domains. You’re recognising that nutrition and sleep are part of an integrated system where each continuously affects the other. Every nutritional choice influences tonight’s sleep. Every night’s sleep influences tomorrow’s food choices.
But also remember that this isn’t about perfection. It’s about understanding which factors matter most and implementing these while ignoring less important details. The modern food environment does make this challenging. Hyperpalatable processed foods are engineered to override satiety. Alcohol is socially normalised. Meal timing gets disrupted by work and social demands. Sleep deprivation drives cravings for exactly the foods that worsen sleep. You’re navigating real obstacles, not imaginary ones.
But within these constraints, you have meaningful agency. You can choose to finish dinner 2-3 hours before bed. You can limit or avoid alcohol. You can prioritise whole foods and adequate nutrients. You can experiment to find what works for your body. Each choice is small. Accumulated consistently, they transform both nutrition and sleep.
I know this stuff can be difficult to put into practice, so here is a rough strategy that you can follow:
Week 1: Fix meal timing. Finish dinner 2.5-3 hours before your target bedtime every night this week. This single change produces meaningful improvements for most people and requires no change to what you eat, only when.
Week 2: Balance your dinner. Ensure adequate protein (25-40g), complex carbohydrates, moderate fats, and vegetables. If your dinners are currently unbalanced, adjust toward better balance.
Week 3: Assess alcohol honestly. If you currently drink in the evening, try eliminating it for one week and notice the difference in sleep quality. This might be the single most impactful change for regular drinkers.
Week 4: Optimise hydration pattern. Front-load water during the day, taper from 7pm onward. Notice if nighttime urination decreases and sleep continuity improves.
After four weeks, you’ve implemented the highest-impact nutritional changes for sleep. If you want to optimise further: assess your total calorie intake and micronutrient intake, and consider supplementing if deficient, experiment with carbohydrate timing at dinner, and consider incorporating sleep-supporting foods whilst avoiding problematic ones.
You don’t need to change everything simultaneously. Start with one foundational change, establish it as habit, then add the next. Progress compounds over time, and imperfect consistency beats perfect planning that never gets implemented.
Feed yourself well. Time your meals appropriately. Support your sleep through nutrition, and your sleep will support your nutrition in return. The positive feedback loop builds from there.
As with everything, there is always more to learn, and we haven’t even begun to scratch the surface with all this stuff. However, if you are interested in staying up to date with all our content, we recommend subscribing to our newsletter and bookmarking our free content page. We do have a lot of content on sleep in our sleep hub.
If you would like more help with your training (or nutrition), we do also have online coaching spaces available.
We also recommend reading our foundational nutrition articles, along with our foundational articles on exercise and stress management, if you really want to learn more about how to optimise your lifestyle. If you want even more free information on sleep, you can follow us on Instagram, YouTube or listen to the podcast, where we discuss all the little intricacies of exercise.
Finally, if you want to learn how to coach nutrition, then consider our Nutrition Coach Certification course. We do also have an exercise program design course, if you are a coach who wants to learn more about effective program design and how to coach it. We do have other courses available too, notably as a sleep course. If you don’t understand something, or you just need clarification, you can always reach out to us on Instagram or via email.
References and Further Reading
Vyazovskiy, V. (2015). Sleep, recovery, and metaregulation: explaining the benefits of sleep. Nature and Science of Sleep, 171. http://doi.org/10.2147/nss.s54036
Sharma, S., & Kavuru, M. (2010). Sleep and Metabolism: An Overview. International Journal of Endocrinology, 2010, 1–12. http://doi.org/10.1155/2010/270832
Yoo, S.-S., Gujar, N., Hu, P., Jolesz, F. A., & Walker, M. P. (2007). The human emotional brain without sleep — a prefrontal amygdala disconnect. Current Biology, 17(20). http://doi.org/10.1016/j.cub.2007.08.007
Copinschi G. Metabolic and endocrine effects of sleep deprivation. Essent Psychopharmacol. 2005;6(6):341-7. PMID: 16459757. https://pubmed.ncbi.nlm.nih.gov/16459757/
Spiegel, K., Leproult, R., L’Hermite-Balériaux, M., Copinschi, G., Penev, P. D., & Cauter, E. V. (2004). Leptin Levels Are Dependent on Sleep Duration: Relationships with Sympathovagal Balance, Carbohydrate Regulation, Cortisol, and Thyrotropin. The Journal of Clinical Endocrinology & Metabolism, 89(11), 5762–5771. http://doi.org/10.1210/jc.2004-1003
Nedeltcheva, A. V., Kilkus, J. M., Imperial, J., Kasza, K., Schoeller, D. A., & Penev, P. D. (2008). Sleep curtailment is accompanied by increased intake of calories from snacks. The American Journal of Clinical Nutrition, 89(1), 126–133. http://doi.org/10.3945/ajcn.2008.26574
Mullington, J. M., Chan, J. L., Dongen, H. P. A. V., Szuba, M. P., Samaras, J., Price, N. J., … Mantzoros, C. S. (2003). Sleep Loss Reduces Diurnal Rhythm Amplitude of Leptin in Healthy Men. Journal of Neuroendocrinology, 15(9), 851–854. http://doi.org/10.1046/j.1365-2826.2003.01069.x
Leproult, R., & Cauter, E. V. (2009). Role of Sleep and Sleep Loss in Hormonal Release and Metabolism. Pediatric Neuroendocrinology Endocrine Development, 11–21. http://doi.org/10.1159/000262524
Spaeth, A. M., Dinges, D. F., & Goel, N. (2013). Effects of Experimental Sleep Restriction on Weight Gain, Caloric Intake, and Meal Timing in Healthy Adults. Sleep, 36(7), 981–990. http://doi.org/10.5665/sleep.2792
Calvin, A. D., Carter, R. E., Adachi, T., Macedo, P. G., Albuquerque, F. N., Walt, C. V. D., … Somers, V. K. (2013). Effects of Experimental Sleep Restriction on Caloric Intake and Activity Energy Expenditure. Chest, 144(1), 79–86. http://doi.org/10.1378/chest.12-2829
Markwald, R. R., Melanson, E. L., Smith, M. R., Higgins, J., Perreault, L., Eckel, R. H., & Wright, K. P. (2013). Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proceedings of the National Academy of Sciences, 110(14), 5695–5700. http://doi.org/10.1073/pnas.1216951110
Cauter, E. V., Spiegel, K., Tasali, E., & Leproult, R. (2008). Metabolic consequences of sleep and sleep loss. Sleep Medicine, 9. http://doi.org/10.1016/s1389-9457(08)70013-3
Spiegel, K., Leproult, R., & Cauter, E. V. (1999). Impact of sleep debt on metabolic and endocrine function. The Lancet, 354(9188), 1435–1439. http://doi.org/10.1016/s0140-6736(99)01376-8
Ness, K. M., Strayer, S. M., Nahmod, N. G., Schade, M. M., Chang, A.-M., Shearer, G. C., & Buxton, O. M. (2019). Four nights of sleep restriction suppress the postprandial lipemic response and decrease satiety. Journal of Lipid Research, 60(11), 1935–1945. http://doi.org/10.1194/jlr.p094375
Hirotsu, C., Tufik, S., & Andersen, M. L. (2015). Interactions between sleep, stress, and metabolism: From physiological to pathological conditions. Sleep Science, 8(3), 143–152. http://doi.org/10.1016/j.slsci.2015.09.002
Morselli, L., Leproult, R., Balbo, M., & Spiegel, K. (2010). Role of sleep duration in the regulation of glucose metabolism and appetite. Best Practice & Research Clinical Endocrinology & Metabolism, 24(5), 687–702. http://doi.org/10.1016/j.beem.2010.07.005
Lamon, S., Morabito, A., Arentson-Lantz, E., Knowles, O., Vincent, G. E., Condo, D., … Aisbett, B. (2020). The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment. http://doi.org/10.1101/2020.03.09.984666
Lipton, J. O., & Sahin, M. (2014). The Neurology of mTOR. Neuron, 84(2), 275–291. http://doi.org/10.1016/j.neuron.2014.09.034
Tudor, J. C., Davis, E. J., Peixoto, L., Wimmer, M. E., Tilborg, E. V., Park, A. J., … Abel, T. (2016). Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis. Science Signaling, 9(425). http://doi.org/10.1126/scisignal.aad4949
Dattilo, M., Antunes, H., Medeiros, A., Neto, M. M., Souza, H., Tufik, S., & Mello, M. D. (2011). Sleep and muscle recovery: Endocrinological and molecular basis for a new and promising hypothesis. Medical Hypotheses, 77(2), 220–222. http://doi.org/10.1016/j.mehy.2011.04.017
Thornton, S. N., & Trabalon, M. (2014). Chronic dehydration is associated with obstructive sleep apnoea syndrome. Clinical Science, 128(3), 225–225. http://doi.org/10.1042/cs20140496
Rosinger, A. Y., Chang, A.-M., Buxton, O. M., Li, J., Wu, S., & Gao, X. (2018). Short sleep duration is associated with inadequate hydration: cross-cultural evidence from US and Chinese adults. Sleep, 42(2). http://doi.org/10.1093/sleep/zsy210
Watson, A. M. (2017). Sleep and Athletic Performance. Current Sports Medicine Reports, 16(6), 413–418. http://doi.org/10.1249/jsr.0000000000000418
Bonnar, D., Bartel, K., Kakoschke, N., & Lang, C. (2018). Sleep Interventions Designed to Improve Athletic Performance and Recovery: A Systematic Review of Current Approaches. Sports Medicine, 48(3), 683–703. http://doi.org/10.1007/s40279-017-0832-x
Saidi, O., Davenne, D., Lehorgne, C., & Duché, P. (2020). Effects of timing of moderate exercise in the evening on sleep and subsequent dietary intake in lean, young, healthy adults: randomized crossover study. European Journal of Applied Physiology, 120(7), 1551–1562. http://doi.org/10.1007/s00421-020-04386-6
Abedelmalek, S., Chtourou, H., Aloui, A., Aouichaoui, C., Souissi, N., & Tabka, Z. (2012). Effect of time of day and partial sleep deprivation on plasma concentrations of IL-6 during a short-term maximal performance. European Journal of Applied Physiology, 113(1), 241–248. http://doi.org/10.1007/s00421-012-2432-7
Azboy, O., & Kaygisiz, Z. (2009). Effects of sleep deprivation on cardiorespiratory functions of the runners and volleyball players during rest and exercise. Acta Physiologica Hungarica, 96(1), 29–36. http://doi.org/10.1556/aphysiol.96.2009.1.3
Bird, S. P. (2013). Sleep, Recovery, and Athletic Performance. Strength and Conditioning Journal, 35(5), 43–47. http://doi.org/10.1519/ssc.0b013e3182a62e2f
Blumert, P. A., Crum, A. J., Ernsting, M., Volek, J. S., Hollander, D. B., Haff, E. E., & Haff, G. G. (2007). The Acute Effects of Twenty-Four Hours of Sleep Loss on the Performance of National-Caliber Male Collegiate Weightlifters. The Journal of Strength and Conditioning Research, 21(4), 1146. http://doi.org/10.1519/r-21606.1
Chase, J. D., Roberson, P. A., Saunders, M. J., Hargens, T. A., Womack, C. J., & Luden, N. D. (2017). One night of sleep restriction following heavy exercise impairs 3-km cycling time-trial performance in the morning. Applied Physiology, Nutrition, and Metabolism, 42(9), 909–915. http://doi.org/10.1139/apnm-2016-0698
Edwards, B. J., & Waterhouse, J. (2009). Effects of One Night of Partial Sleep Deprivation upon Diurnal Rhythms of Accuracy and Consistency in Throwing Darts. Chronobiology International, 26(4), 756–768. http://doi.org/10.1080/07420520902929037
Fullagar, H. H. K., Skorski, S., Duffield, R., Hammes, D., Coutts, A. J., & Meyer, T. (2014). Sleep and Athletic Performance: The Effects of Sleep Loss on Exercise Performance, and Physiological and Cognitive Responses to Exercise. Sports Medicine, 45(2), 161–186. http://doi.org/10.1007/s40279-014-0260-0
Gupta, L., Morgan, K., & Gilchrist, S. (2016). Does Elite Sport Degrade Sleep Quality? A Systematic Review. Sports Medicine, 47(7), 1317–1333. http://doi.org/10.1007/s40279-016-0650-6
Hausswirth, C., Louis, J., Aubry, A., Bonnet, G., Duffield, R., & Meur, Y. L. (2014). Evidence of Disturbed Sleep and Increased Illness in Overreached Endurance Athletes. Medicine & Science in Sports & Exercise, 46(5), 1036–1045. http://doi.org/10.1249/mss.0000000000000177
Mah, C. D., Mah, K. E., Kezirian, E. J., & Dement, W. C. (2011). The Effects of Sleep Extension on the Athletic Performance of Collegiate Basketball Players. Sleep, 34(7), 943–950. http://doi.org/10.5665/sleep.1132
Milewski, M. D., Skaggs, D. L., Bishop, G. A., Pace, J. L., Ibrahim, D. A., Wren, T. A., & Barzdukas, A. (2014). Chronic Lack of Sleep is Associated With Increased Sports Injuries in Adolescent Athletes. Journal of Pediatric Orthopaedics, 34(2), 129–133. http://doi.org/10.1097/bpo.0000000000000151
Mougin, F., Bourdin, H., Simon-Rigaud, M., Didier, J., Toubin, G., & Kantelip, J. (1996). Effects of a Selective Sleep Deprivation on Subsequent Anaerobic Performance. International Journal of Sports Medicine, 17(02), 115–119. http://doi.org/10.1055/s-2007-972818
Oliver, S. J., Costa, R. J. S., Laing, S. J., Bilzon, J. L. J., & Walsh, N. P. (2009). One night of sleep deprivation decreases treadmill endurance performance. European Journal of Applied Physiology, 107(2), 155–161. http://doi.org/10.1007/s00421-009-1103-9
Pallesen, S., Gundersen, H. S., Kristoffersen, M., Bjorvatn, B., Thun, E., & Harris, A. (2017). The Effects of Sleep Deprivation on Soccer Skills. Perceptual and Motor Skills, 124(4), 812–829. http://doi.org/10.1177/0031512517707412
Reilly, T., & Piercy, M. (1994). The effect of partial sleep deprivation on weight-lifting performance. Ergonomics, 37(1), 107–115. http://doi.org/10.1080/00140139408963628
Rossa, K. R., Smith, S. S., Allan, A. C., & Sullivan, K. A. (2014). The Effects of Sleep Restriction on Executive Inhibitory Control and Affect in Young Adults. Journal of Adolescent Health, 55(2), 287–292. http://doi.org/10.1016/j.jadohealth.2013.12.034
Sargent, C., & Roach, G. D. (2016). Sleep duration is reduced in elite athletes following night-time competition. Chronobiology International, 33(6), 667–670. http://doi.org/10.3109/07420528.2016.1167715
Skein, M., Duffield, R., Edge, J., Short, M. J., & Mündel, T. (2011). Intermittent-Sprint Performance and Muscle Glycogen after 30 h of Sleep Deprivation. Medicine & Science in Sports & Exercise, 43(7), 1301–1311. http://doi.org/10.1249/mss.0b013e31820abc5a
Souissi, N., Sesboüé, B., Gauthier, A., Larue, J., & Davenne, D. (2003). Effects of one nights sleep deprivation on anaerobic performance the following day. European Journal of Applied Physiology, 89(3), 359–366. http://doi.org/10.1007/s00421-003-0793-7
Caia, J., Kelly, V. G., & Halson, S. L. (2017). The role of sleep in maximising performance in elite athletes. Sport, Recovery, and Performance, 151–167. http://doi.org/10.4324/9781315268149-11
Alley, J. R., Mazzochi, J. W., Smith, C. J., Morris, D. M., & Collier, S. R. (2015). Effects of Resistance Exercise Timing on Sleep Architecture and Nocturnal Blood Pressure. Journal of Strength and Conditioning Research, 29(5), 1378–1385. http://doi.org/10.1519/jsc.0000000000000750
Kovacevic, A., Mavros, Y., Heisz, J. J., & Singh, M. A. F. (2018). The effect of resistance exercise on sleep: A systematic review of randomized controlled trials. Sleep Medicine Reviews, 39, 52–68. http://doi.org/10.1016/j.smrv.2017.07.002
Herrick, J. E., Puri, S., & Richards, K. C. (2017). Resistance training does not alter same-day sleep architecture in institutionalized older adults. Journal of Sleep Research, 27(4). http://doi.org/10.1111/jsr.12590
Edinger, J. D., Morey, M. C., Sullivan, R. J., Higginbotham, M. B., Marsh, G. R., Dailey, D. S., & McCall, W. V. (1993). Aerobic fitness, acute exercise and sleep in older men. Sleep, 16(4), 351-359. https://doi.org/10.1093/sleep/16.4.351
King, A. C. (1997). Moderate-intensity exercise and self-rated quality of sleep in older adults. A randomized controlled trial. JAMA: The Journal of the American Medical Association, 277(1), 32–37. http://doi.org/10.1001/jama.277.1.32
Passos, G. S., Poyares, D., Santana, M. G., Garbuio, S. A., Tufik, S., & Mello, M. T. (2010). Effect of Acute Physical Exercise on Patients with Chronic Primary Insomnia. Journal of Clinical Sleep Medicine, 06(03), 270–275. http://doi.org/10.5664/jcsm.27825
Reid, K. J., Baron, K. G., Lu, B., Naylor, E., Wolfe, L., & Zee, P. C. (2010). Aerobic exercise improves self-reported sleep and quality of life in older adults with insomnia. Sleep Medicine, 11(9), 934–940. http://doi.org/10.1016/j.sleep.2010.04.014
Viana, V. A. R., Esteves, A. M., Boscolo, R. A., Grassmann, V., Santana, M. G., Tufik, S., & Mello, M. T. D. (2011). The effects of a session of resistance training on sleep patterns in the elderly. European Journal of Applied Physiology, 112(7), 2403–2408. http://doi.org/10.1007/s00421-011-2219-2
Herring, M., Kline, C., & Oconnor, P. (2015). Effects of Exercise Training On Self-reported Sleep Among Young Women with Generalized Anxiety Disorder (GAD). European Psychiatry, 30, 465. http://doi.org/10.1016/s0924-9338(15)31893-9
Kredlow, M. A., Capozzoli, M. C., Hearon, B. A., Calkins, A. W., & Otto, M. W. (2015). The effects of physical activity on sleep: a meta-analytic review. Journal of Behavioral Medicine, 38(3), 427–449. http://doi.org/10.1007/s10865-015-9617-6
Yang, P.-Y., Ho, K.-H., Chen, H.-C., & Chien, M.-Y. (2012). Exercise training improves sleep quality in middle-aged and older adults with sleep problems: a systematic review. Journal of Physiotherapy, 58(3), 157–163. http://doi.org/10.1016/s1836-9553(12)70106-6
Kline, C. E., Sui, X., Hall, M. H., Youngstedt, S. D., Blair, S. N., Earnest, C. P., & Church, T. S. (2012). Dose–response effects of exercise training on the subjective sleep quality of postmenopausal women: exploratory analyses of a randomised controlled trial. BMJ Open, 2(4). http://doi.org/10.1136/bmjopen-2012-001044
Fairbrother, K., Cartner, B. W., Triplett, N., Morris, D. M., & Collier, S. R. (2011). The Effects of Aerobic Exercise Timing on Sleep Architecture. Medicine & Science in Sports & Exercise, 43(Suppl 1), 879. http://doi.org/10.1249/01.mss.0000402452.16375.20
Youngstedt, S. D., & Kline, C. E. (2006). Epidemiology of exercise and sleep. Sleep and Biological Rhythms, 4(3), 215–221. http://doi.org/10.1111/j.1479-8425.2006.00235.x
Stenholm, S., Head, J., Kivimäki, M., Hanson, L. L. M., Pentti, J., Rod, N. H., … Vahtera, J. (2018). Sleep Duration and Sleep Disturbances as Predictors of Healthy and Chronic Disease–Free Life Expectancy Between Ages 50 and 75: A Pooled Analysis of Three Cohorts. The Journals of Gerontology: Series A, 74(2), 204–210. http://doi.org/10.1093/gerona/gly01
Xiao, Q., Keadle, S. K., Hollenbeck, A. R., & Matthews, C. E. (2014). Sleep Duration and Total and Cause-Specific Mortality in a Large US Cohort: Interrelationships With Physical Activity, Sedentary Behavior, and Body Mass Index. American Journal of Epidemiology, 180(10), 997–1006. http://doi.org/10.1093/aje/kwu222
Reynolds, A. C., Dorrian, J., Liu, P. Y., Dongen, H. P. A. V., Wittert, G. A., Harmer, L. J., & Banks, S. (2012). Impact of Five Nights of Sleep Restriction on Glucose Metabolism, Leptin and Testosterone in Young Adult Men. PLoS ONE, 7(7). http://doi.org/10.1371/journal.pone.0041218
Åkerstedt, T., Palmblad, J., Torre, B. D. L., Marana, R., & Gillberg, M. (1980). Adrenocortical and Gonadal Steroids During Sleep Deprivation. Sleep, 3(1), 23–30. http://doi.org/10.1093/sleep/3.1.23
Cortés-Gallegos, V., Castañeda, G., Alonso, R., Sojo, I., Carranco, A., Cervantes, C., & Parra, A. (1983). Sleep Deprivation Reduces Circulating Androgens in Healthy Men. Archives of Andrology, 10(1), 33–37. http://doi.org/10.3109/01485018308990167
González-Santos, M. R., Gajá-Rodíguez, O. V., Alonso-Uriarte, R., Sojo-Aranda, I., & Cortés-Gallegos, V. (1989). Sleep Deprivation and Adaptive Hormonal Responses of Healthy Men. Archives of Andrology, 22(3), 203–207. http://doi.org/10.3109/01485018908986773
Penev, P. D. (2007). Association Between Sleep and Morning Testosterone Levels In Older Men. Sleep, 30(4), 427–432. http://doi.org/10.1093/sleep/30.4.427
Kloss, J. D., Perlis, M. L., Zamzow, J. A., Culnan, E. J., & Gracia, C. R. (2015). Sleep, sleep disturbance, and fertility in women. Sleep Medicine Reviews, 22, 78–87. http://doi.org/10.1016/j.smrv.2014.10.005
Mahoney, M. M. (2010). Shift Work, Jet Lag, and Female Reproduction. International Journal of Endocrinology, 2010, 1–9. http://doi.org/10.1155/2010/813764
Labyak, S., Lava, S., Turek, F., & Zee, P. (2002). Effects Of Shiftwork On Sleep And Menstrual Function In Nurses. Health Care for Women International, 23(6-7), 703–714. http://doi.org/10.1080/07399330290107449
Pal, L., Bevilacqua, K., Zeitlian, G., Shu, J., & Santoro, N. (2008). Implications of diminished ovarian reserve (DOR) extend well beyond reproductive concerns. Menopause, 15(6), 1086–1094. http://doi.org/10.1097/gme.0b013e3181728467
Axelsson, G., Rylander, R., & Molin, I. (1989). Outcome of pregnancy in relation to irregular and inconvenient work schedules. Occupational and Environmental Medicine, 46(6), 393–398. http://doi.org/10.1136/oem.46.6.393
Bisanti, L., Olsen, J., Basso, O., Thonneau, P., & Karmaus, W. (1996). Shift Work and Subfecundity: A European Multicenter Study. Journal of Occupational & Environmental Medicine, 38(4), 352–358. http://doi.org/10.1097/00043764-199604000-00012
Rossmanith, W. G. (1998). The impact of sleep on gonadotropin secretion. Gynecological Endocrinology, 12(6), 381–389. http://doi.org/10.3109/09513599809012840
Fernando, S., & Rombauts, L. (2014). Melatonin: shedding light on infertility? – a review of the recent literature. Journal of Ovarian Research, 7(1). http://doi.org/10.1186/s13048-014-0098-y
Rocha, C., Rato, L., Martins, A., Alves, M., & Oliveira, P. (2015). Melatonin and Male Reproductive Health: Relevance of Darkness and Antioxidant Properties. Current Molecular Medicine, 15(4), 299–311. http://doi.org/10.2174/1566524015666150505155530
Song, C., Peng, W., Yin, S., Zhao, J., Fu, B., Zhang, J., … Zhang, Y. (2016). Melatonin improves age-induced fertility decline and attenuates ovarian mitochondrial oxidative stress in mice. Scientific Reports, 6(1). http://doi.org/10.1038/srep35165
Espino, J., Macedo, M., Lozano, G., Ortiz, Á., Rodríguez, C., Rodríguez, A. B., & Bejarano, I. (2019). Impact of Melatonin Supplementation in Women with Unexplained Infertility Undergoing Fertility Treatment. Antioxidants, 8(9), 338. http://doi.org/10.3390/antiox8090338
Tamura, H., Takasaki, A., Taketani, T., Tanabe, M., Kizuka, F., Lee, L., … Sugino, N. (2012). The role of melatonin as an antioxidant in the follicle. Journal of Ovarian Research, 5(1), 5. http://doi.org/10.1186/1757-2215-5-5
Saaresranta, T., & Polo, O. (2003). Sleep-disordered breathing and hormones. European Respiratory Journal, 22(1), 161–172. http://doi.org/10.1183/09031936.03.00062403
Cappuccio, F. P., Cooper, D., Delia, L., Strazzullo, P., & Miller, M. A. (2011). Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies. European Heart Journal, 32(12), 1484–1492. http://doi.org/10.1093/eurheartj/ehr007
Jansen, E. C., Dunietz, G. L., Tsimpanouli, M.-E., Guyer, H. M., Shannon, C., Hershner, S. D., … Baylin, A. (2018). Sleep, Diet, and Cardiometabolic Health Investigations: a Systematic Review of Analytic Strategies. Current Nutrition Reports, 7(4), 235–258. http://doi.org/10.1007/s13668-018-0240-3
Knutson, K. L., Cauter, E. V., Rathouz, P. J., Yan, L. L., Hulley, S. B., Liu, K., & Lauderdale, D. S. (2009). Association Between Sleep and Blood Pressure in Midlife. Archives of Internal Medicine, 169(11), 1055. http://doi.org/10.1001/archinternmed.2009.119
Besedovsky, L., Lange, T., & Born, J. (2011). Sleep and immune function. Pflügers Archiv – European Journal of Physiology, 463(1), 121–137. http://doi.org/10.1007/s00424-011-1044-0
Besedovsky, L., Lange, T., & Haack, M. (2019). The Sleep-Immune Crosstalk in Health and Disease. Physiological Reviews, 99(3), 1325–1380. http://doi.org/10.1152/physrev.00010.2018
Orr, W. C., Fass, R., Sundaram, S. S., & Scheimann, A. O. (2020). The effect of sleep on gastrointestinal functioning in common digestive diseases. The Lancet Gastroenterology & Hepatology, 5(6), 616–624. http://doi.org/10.1016/s2468-1253(19)30412-1
Tang, Y., Preuss, F., Turek, F. W., Jakate, S., & Keshavarzian, A. (2009). Sleep deprivation worsens inflammation and delays recovery in a mouse model of colitis. Sleep Medicine, 10(6), 597–603. http://doi.org/10.1016/j.sleep.2008.12.009
Chen, Y., Tan, F., Wei, L., Li, X., Lyu, Z., Feng, X., … Li, N. (2018). Sleep duration and the risk of cancer: a systematic review and meta-analysis including dose–response relationship. BMC Cancer, 18(1). http://doi.org/10.1186/s12885-018-5025-y
Almendros, I., Martinez-Garcia, M. A., Farré, R., & Gozal, D. (2020). Obesity, sleep apnea, and cancer. International Journal of Obesity, 44(8), 1653–1667. http://doi.org/10.1038/s41366-020-0549-z
Erren, T. C., Falaturi, P., Morfeld, P., Knauth, P., Reiter, R. J., & Piekarski, C. (2010). Shift Work and Cancer. Deutsches Aerzteblatt Online. http://doi.org/10.3238/arztebl.2010.0657
Bernert, R. A., Kim, J. S., Iwata, N. G., & Perlis, M. L. (2015). Sleep Disturbances as an Evidence-Based Suicide Risk Factor. Current Psychiatry Reports, 17(3). http://doi.org/10.1007/s11920-015-0554-4
Kim, J.-H., Park, E.-C., Cho, W.-H., Park, J.-Y., Choi, W.-J., & Chang, H.-S. (2013). Association between Total Sleep Duration and Suicidal Ideation among the Korean General Adult Population. Sleep, 36(10), 1563–1572. http://doi.org/10.5665/sleep.3058
Mccall, W. V., & Black, C. G. (2013). The Link Between Suicide and Insomnia: Theoretical Mechanisms. Current Psychiatry Reports, 15(9). http://doi.org/10.1007/s11920-013-0389-9
Li, S. X., Lam, S. P., Zhang, J., Yu, M. W. M., Chan, J. W. Y., Chan, C. S. Y., … Wing, Y.-K. (2016). Sleep Disturbances and Suicide Risk in an 8-Year Longitudinal Study of Schizophrenia-Spectrum Disorders. Sleep, 39(6), 1275–1282. http://doi.org/10.5665/sleep.5852
Littlewood, D. L., Gooding, P., Kyle, S. D., Pratt, D., & Peters, S. (2016). Understanding the role of sleep in suicide risk: qualitative interview study. BMJ Open, 6(8). http://doi.org/10.1136/bmjopen-2016-012113
Lin, H.-T., Lai, C.-H., Perng, H.-J., Chung, C.-H., Wang, C.-C., Chen, W.-L., & Chien, W.-C. (2018). Insomnia as an independent predictor of suicide attempts: a nationwide population-based retrospective cohort study. BMC Psychiatry, 18(1). http://doi.org/10.1186/s12888-018-1702-2
Freeman, D., Sheaves, B., Waite, F., Harvey, A. G., & Harrison, P. J. (2020). Sleep disturbance and psychiatric disorders. The Lancet Psychiatry, 7(7), 628–637. http://doi.org/10.1016/s2215-0366(20)30136-x
Benca, R. M. (1992). Sleep and Psychiatric Disorders. Archives of General Psychiatry, 49(8), 651. http://doi.org/10.1001/archpsyc.1992.01820080059010
Breslau, N., Roth, T., Rosenthal, L., & Andreski, P. (1996). Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults. Biological Psychiatry, 39(6), 411–418. http://doi.org/10.1016/0006-3223(95)00188-3
Baglioni, C., Nanovska, S., Regen, W., Spiegelhalder, K., Feige, B., Nissen, C., … Riemann, D. (2016). Sleep and mental disorders: A meta-analysis of polysomnographic research. Psychological Bulletin, 142(9), 969–990. http://doi.org/10.1037/bul0000053
Goldstein, A. N., & Walker, M. P. (2014). The Role of Sleep in Emotional Brain Function. Annual Review of Clinical Psychology, 10(1), 679–708. http://doi.org/10.1146/annurev-clinpsy-032813-153716
Postuma, R. B., Iranzo, A., Hu, M., Högl, B., Boeve, B. F., Manni, R., … Pelletier, A. (2019). Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study. Brain, 142(3), 744–759. http://doi.org/10.1093/brain/awz030
Wintler, T., Schoch, H., Frank, M. G., & Peixoto, L. (2020). Sleep, brain development, and autism spectrum disorders: Insights from animal models. Journal of Neuroscience Research, 98(6), 1137–1149. http://doi.org/10.1002/jnr.24619
Shokri-Kojori, E., Wang, G.-J., Wiers, C. E., Demiral, S. B., Guo, M., Kim, S. W., … Volkow, N. D. (2018). β-Amyloid accumulation in the human brain after one night of sleep deprivation. Proceedings of the National Academy of Sciences, 115(17), 4483–4488. http://doi.org/10.1073/pnas.1721694115
Mantovani, S., Smith, S. S., Gordon, R., & Osullivan, J. D. (2018). An overview of sleep and circadian dysfunction in Parkinsons disease. Journal of Sleep Research, 27(3). http://doi.org/10.1111/jsr.12673
Malhotra, R. K. (2018). Neurodegenerative Disorders and Sleep. Sleep Medicine Clinics, 13(1), 63–70. http://doi.org/10.1016/j.jsmc.2017.09.006
Huang, L.-B., Tsai, M.-C., Chen, C.-Y., & Hsu, S.-C. (2013). The Effectiveness of Light/Dark Exposure to Treat Insomnia in Female Nurses Undertaking Shift Work during the Evening/Night Shift. Journal of Clinical Sleep Medicine, 09(07), 641–646. http://doi.org/10.5664/jcsm.2824
Zhang, Y., & Papantoniou, K. (2019). Night shift work and its carcinogenicity. The Lancet Oncology, 20(10). http://doi.org/10.1016/s1470-2045(19)30578-9
Perry-Jenkins, M., Goldberg, A. E., Pierce, C. P., & Sayer, A. G. (2007). Shift Work, Role Overload, and the Transition to Parenthood. Journal of Marriage and Family, 69(1), 123–138. http://doi.org/10.1111/j.1741-3737.2006.00349.x
Rodziewicz TL, Hipskind JE. Medical Error Prevention. 2020 May 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. PMID: 29763131. https://pubmed.ncbi.nlm.nih.gov/29763131/
Tanaka, K., Takahashi, M., Hiro, H., Kakinuma, M., Tanaka, M., Kamata, N., & Miyaoka, H. (2010). Differences in Medical Error Risk among Nurses Working Two- and Three-shift Systems at Teaching Hospitals: A Six-month Prospective Study. Industrial Health, 48(3), 357–364. http://doi.org/10.2486/indhealth.48.357
Admi H, Tzischinsky O, Epstein R, Herer P, Lavie P. Shift work in nursing: is it really a risk factor for nurses’ health and patients’ safety?. Nurs Econ. 2008;26(4):250-257. https://pubmed.ncbi.nlm.nih.gov/18777974/
Clendon, J., & Gibbons, V. (2015). 12h shifts and rates of error among nurses: A systematic review. International Journal of Nursing Studies, 52(7), 1231–1242. http://doi.org/10.1016/j.ijnurstu.2015.03.011
Hammadah, M., Kindya, B. R., Allard‐Ratick, M. P., Jazbeh, S., Eapen, D., Tang, W. W., & Sperling, L. (2017). Navigating air travel and cardiovascular concerns: Is the sky the limit?, Clinical Cardiology, 40 (9), 660–666. http://doi.org/10.1002/clc.22741
Lieber, B. A., Han, J., Appelboom, G., Taylor, B. E., Han, B., Agarwal, N., & Connolly, E. S. (2016). Association of Steroid Use with Deep Venous Thrombosis and Pulmonary Embolism in Neurosurgical Patients: A National Database Analysis. World Neurosurgery, 89, 126–132. http://doi.org/10.1016/j.wneu.2016.01.033
El-Menyar, A., Asim, M., & Al-Thani, H. (2017). Obesity Paradox in Patients With Deep Venous Thrombosis. Clinical and Applied Thrombosis/Hemostasis, 24(6), 986–992. http://doi.org/10.1177/1076029617727858
Klovaite, J., Benn, M., & Nordestgaard, B. G. (2014). Obesity as a causal risk factor for deep venous thrombosis: a Mendelian randomization study. Journal of Internal Medicine, 277(5), 573–584. http://doi.org/10.1111/joim.12299
Davies, H. O., Popplewell, M., Singhal, R., Smith, N., & Bradbury, A. W. (2016). Obesity and lower limb venous disease – The epidemic of phlebesity. Phlebology: The Journal of Venous Disease, 32(4), 227–233. http://doi.org/10.1177/0268355516649333
Liljeqvist, S., Helldén, A., Bergman, U., & Söderberg, M. (2008). Pulmonary embolism associated with the use of anabolic steroids. European Journal of Internal Medicine, 19(3), 214–215. http://doi.org/10.1016/j.ejim.2007.03.016
Linton MF, Yancey PG, Davies SS, Jerome WG (Jay), Linton EF, Vickers KC. The Role of Lipids and Lipoproteins in Atherosclerosis. In: De Groot LJ, Chrousos G, Dungan K, et al., eds. Endotext. South Dartmouth (MA): MDText.com, Inc.; 2000. http://www.ncbi.nlm.nih.gov/books/NBK343489/.
Rescheduling of meals may ease the effects of jet lag. (2017). Nursing Standard, 31(48), 16–16. http://doi.org/10.7748/ns.31.48.16.s17
Ruscitto, C., & Ogden, J. (2016). The impact of an implementation intention to improve mealtimes and reduce jet lag in long-haul cabin crew. Psychology & Health, 32(1), 61–77. http://doi.org/10.1080/08870446.2016.1240174
Reid, K. J., & Abbott, S. M. (2015). Jet Lag and Shift Work Disorder. Sleep Medicine Clinics, 10(4), 523–535. http://doi.org/10.1016/j.jsmc.2015.08.006
Srinivasan, V., Spence, D. W., Pandi-Perumal, S. R., Trakht, I., & Cardinali, D. P. (2008). Jet lag: Therapeutic use of melatonin and possible application of melatonin analogs. Travel Medicine and Infectious Disease, 6(1-2), 17–28. http://doi.org/10.1016/j.tmaid.2007.12.002
Edwards, B. J., Atkinson, G., Waterhouse, J., Reilly, T., Godfrey, R., & Budgett, R. (2000). Use of melatonin in recovery from jet-lag following an eastward flight across 10 time-zones. Ergonomics, 43(10), 1501–1513. http://doi.org/10.1080/001401300750003934
Zee, P. C., & Goldstein, C. A. (2010). Treatment of Shift Work Disorder and Jet Lag. Current Treatment Options in Neurology, 12(5), 396–411. http://doi.org/10.1007/s11940-010-0090-9
https://www.nhlbi.nih.gov/health-topics/circadian-rhythm-disorders
Borodkin, K., & Dagan, Y. (2013). Diagnostic Algorithm for Circadian Rhythm Sleep Disorders. Encyclopedia of Sleep, 66–73. http://doi.org/10.1016/b978-0-12-378610-4.00284-9
Lockley, S. (2013). Special Considerations and Future Directions in Circadian Rhythm Sleep Disorders Diagnosis. Encyclopedia of Sleep, 138–149. http://doi.org/10.1016/b978-0-12-378610-4.00299-0
Crowley, S., & Youngstedt, S. (2013). Pathophysiology, Associations, and Consequences of Circadian Rhythm Sleep Disorder. Encyclopedia of Sleep, 16–21. http://doi.org/10.1016/b978-0-12-378610-4.00266-7
Franken, P., & Dijk, D.-J. (2009). Circadian clock genes and sleep homeostasis. European Journal of Neuroscience, 29(9), 1820–1829. http://doi.org/10.1111/j.1460-9568.2009.06723.x
Burgess, H. J., & Emens, J. S. (2016). Circadian-Based Therapies for Circadian Rhythm Sleep-Wake Disorders. Current Sleep Medicine Reports, 2(3), 158–165. http://doi.org/10.1007/s40675-016-0052-1
Jones, C. R., Huang, A. L., Ptáček, L. J., & Fu, Y.-H. (2013). Genetic basis of human circadian rhythm disorders. Experimental Neurology, 243, 28–33. http://doi.org/10.1016/j.expneurol.2012.07.012
Toh KL. Basic science review on circadian rhythm biology and circadian sleep disorders. Ann Acad Med Singap. 2008;37(8):662-668. https://pubmed.ncbi.nlm.nih.gov/18797559/
Farhud D, Aryan Z. Circadian Rhythm, Lifestyle and Health: A Narrative Review. Iran J Public Health. 2018;47(8):1068-1076. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123576/
Dodson, E. R., & Zee, P. C. (2010). Therapeutics for Circadian Rhythm Sleep Disorders. Sleep Medicine Clinics, 5(4), 701–715. http://doi.org/10.1016/j.jsmc.2010.08.001
Zhu, L., & Zee, P. C. (2012). Circadian Rhythm Sleep Disorders. Neurologic Clinics, 30(4), 1167–1191. http://doi.org/10.1016/j.ncl.2012.08.011
Kim MJ, Lee JH, Duffy JF. Circadian Rhythm Sleep Disorders. J Clin Outcomes Manag. 2013;20(11):513-528. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212693/
Zhong, G., Naismith, S. L., Rogers, N. L., & Lewis, S. J. G. (2011). Sleep-wake disturbances in common neurodegenerative diseases: A closer look at selected aspects of the neural circuitry. Journal of the Neurological Sciences, 307(1-2), 9–14. http://doi.org/10.1016/j.jns.2011.04.020
Dijk, D.-J., Boulos, Z., Eastman, C. I., Lewy, A. J., Campbell, S. S., & Terman, M. (1995). Light Treatment for Sleep Disorders: Consensus Report. Journal of Biological Rhythms, 10(2), 113–125. http://doi.org/10.1177/074873049501000204
Barion, A., & Zee, P. C. (2007). A clinical approach to circadian rhythm sleep disorders. Sleep Medicine, 8(6), 566–577. http://doi.org/10.1016/j.sleep.2006.11.017
Horne JA, Ostberg O. A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms. Int J Chronobiol. 1976;4(2):97-110. https://pubmed.ncbi.nlm.nih.gov/1027738/
Adan, A., & Almirall, H. (1991). Horne & Östberg morningness-eveningness questionnaire: A reduced scale. Personality and Individual Differences, 12(3), 241–253. http://doi.org/10.1016/0191-8869(91)90110-w
Urbán, R., Magyaródi, T., & Rigó, A. (2011). Morningness-Eveningness, Chronotypes and Health-Impairing Behaviors in Adolescents. Chronobiology International, 28(3), 238–247. http://doi.org/10.3109/07420528.2010.549599
https://www.thewep.org/documentations/mctq
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989). The Pittsburgh sleep quality index: A new instrument for psychiatric practice and research. Psychiatry Research, 28(2), 193–213. http://doi.org/10.1016/0165-1781(89)90047-4
Bastien, C. (2001). Validation of the Insomnia Severity Index as an outcome measure for insomnia research. Sleep Medicine, 2(4), 297–307. http://doi.org/10.1016/s1389-9457(00)00065-4
Yang, M., Morin, C. M., Schaefer, K., & Wallenstein, G. V. (2009). Interpreting score differences in the Insomnia Severity Index: using health-related outcomes to define the minimally important difference. Current Medical Research and Opinion, 25(10), 2487–2494. http://doi.org/10.1185/03007990903167415
Morin, C. M., Belleville, G., Bélanger, L., & Ivers, H. (2011). The Insomnia Severity Index: Psychometric Indicators to Detect Insomnia Cases and Evaluate Treatment Response. Sleep, 34(5), 601–608. http://doi.org/10.1093/sleep/34.5.601
Castriotta RJ, Wilde MC, Lai JM, Atanasov S, Masel BE, Kuna ST. Prevalence and consequences of sleep disorders in traumatic brain injury. J Clin Sleep Med. 2007;3(4):349-356. https://pubmed.ncbi.nlm.nih.gov/17694722/
Chokroverty S. Overview of sleep & sleep disorders. Indian J Med Res. 2010;131:126-140. https://pubmed.ncbi.nlm.nih.gov/20308738/
Pavlova, M. K., & Latreille, V. (2019). Sleep Disorders. The American Journal of Medicine, 132(3), 292–299. http://doi.org/10.1016/j.amjmed.2018.09.021
Olejniczak, P. W., & Fisch, B. J. (2003). Sleep disorders. Medical Clinics of North America, 87(4), 803–833. http://doi.org/10.1016/s0025-7125(03)00006-3
https://www.nhlbi.nih.gov/health-topics/sleep-apnea
https://clevemed.com/what-is-sleep-apnea/patient-sleep-apnea-screener/
Spicuzza, L., Caruso, D., & Maria, G. D. (2015). Obstructive sleep apnoea syndrome and its management. Therapeutic Advances in Chronic Disease, 6(5), 273–285. http://doi.org/10.1177/2040622315590318
Bixler, E. O., Vgontzas, A. N., Lin, H.-M., Liao, D., Calhoun, S., Fedok, F., … Graff, G. (2008). Blood Pressure Associated With Sleep-Disordered Breathing in a Population Sample of Children. Hypertension, 52(5), 841–846. http://doi.org/10.1161/hypertensionaha.108.116756
Campos, A. I., García-Marín, L. M., Byrne, E. M., Martin, N. G., Cuéllar-Partida, G., & Rentería, M. E. (2020). Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank. Nature Communications, 11(1). http://doi.org/10.1038/s41467-020-14625-1
Morgenthaler, T. I., Kagramanov, V., Hanak, V., & Decker, P. A. (2006). Complex Sleep Apnea Syndrome: Is It a Unique Clinical Syndrome? Sleep, 29(9), 1203–1209. http://doi.org/10.1093/sleep/29.9.1203
El-Ad, B., & Lavie, P. (2005). Effect of sleep apnea on cognition and mood. International Review of Psychiatry, 17(4), 277–282. http://doi.org/10.1080/09540260500104508
Morgenstern, M., Wang, J., Beatty, N., Batemarco, T., Sica, A. L., & Greenberg, H. (2014). Obstructive Sleep Apnea. Endocrinology and Metabolism Clinics of North America, 43(1), 187–204. http://doi.org/10.1016/j.ecl.2013.09.002
Sleep–Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research. (1999). Sleep, 22(5), 667–689. http://doi.org/10.1093/sleep/22.5.667
Ruehland, W. R., Rochford, P. D., O’Donoghue, F. J., Pierce, R. J., Singh, P., & Thornton, A. T. (2009). The New AASM Criteria for Scoring Hypopneas: Impact on the Apnea Hypopnea Index. Sleep, 32(2), 150–157. http://doi.org/10.1093/sleep/32.2.150
Selim, B. J., Koo, B. B., Qin, L., Jeon, S., Won, C., Redeker, N. S., … Yaggi, H. K. (2016). The Association between Nocturnal Cardiac Arrhythmias and Sleep-Disordered Breathing: The DREAM Study. Journal of Clinical Sleep Medicine, 12(06), 829–837. http://doi.org/10.5664/jcsm.5880
Ahmed, M. H. (2010). Obstructive sleep apnea syndrome and fatty liver: Association or causal link? World Journal of Gastroenterology, 16(34), 4243. http://doi.org/10.3748/wjg.v16.i34.4243
Singh, H., Pollock, R., Uhanova, J., Kryger, M., Hawkins, K., & Minuk, G. Y. (2005). Symptoms of Obstructive Sleep Apnea in Patients with Nonalcoholic Fatty Liver Disease. Digestive Diseases and Sciences, 50(12), 2338–2343. http://doi.org/10.1007/s10620-005-3058-y
Lawati, N. M. A., Patel, S. R., & Ayas, N. T. (2009). Epidemiology, Risk Factors, and Consequences of Obstructive Sleep Apnea and Short Sleep Duration. Progress in Cardiovascular Diseases, 51(4), 285–293. http://doi.org/10.1016/j.pcad.2008.08.001
Young, T. (2004). Risk Factors for Obstructive Sleep Apnea in Adults. Jama, 291(16), 2013. http://doi.org/10.1001/jama.291.16.2013
Yaggi, H. K., Concato, J., Kernan, W. N., Lichtman, J. H., Brass, L. M., & Mohsenin, V. (2005). Obstructive Sleep Apnea as a Risk Factor for Stroke and Death. New England Journal of Medicine, 353(19), 2034–2041. http://doi.org/10.1056/nejmoa043104
Redline, S., Budhiraja, R., Kapur, V., Marcus, C. L., Mateika, J. H., Mehra, R., … Quan, A. S. F. (2007). The Scoring of Respiratory Events in Sleep: Reliability and Validity. Journal of Clinical Sleep Medicine, 03(02), 169–200. http://doi.org/10.5664/jcsm.26818
Basheer B, Hegde KS, Bhat SS, Umar D, Baroudi K. Influence of mouth breathing on the dentofacial growth of children: a cephalometric study. J Int Oral Health. 2014;6(6):50-55. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295456/
Ruhle, K. H., & Nilius, G. (2008). Mouth Breathing in Obstructive Sleep Apnea prior to and during Nasal Continuous Positive Airway Pressure. Respiration, 76(1), 40–45. http://doi.org/10.1159/000111806
Izu, S. C., Itamoto, C. H., Pradella-Hallinan, M., Pizarro, G. U., Tufik, S., Pignatari, S., & Fujita, R. R. (2010). Obstructive sleep apnea syndrome (OSAS) in mouth breathing children. Brazilian Journal of Otorhinolaryngology, 76(5), 552–556. http://doi.org/10.1590/s1808-86942010000500003
Lee, S. H., Choi, J. H., Shin, C., Lee, H. M., Kwon, S. Y., & Lee, S. H. (2007). How Does Open-Mouth Breathing Influence Upper Airway Anatomy? The Laryngoscope, 117(6), 1102–1106. http://doi.org/10.1097/mlg.0b013e318042aef7
Tuomilehto, H. P. I., Seppä, J. M., Partinen, M. M., Peltonen, M., Gylling, H., Tuomilehto, J. O. I., … Uusitupa, M. (2009). Lifestyle Intervention with Weight Reduction. American Journal of Respiratory and Critical Care Medicine, 179(4), 320–327. http://doi.org/10.1164/rccm.200805-669oc
https://www.cdc.gov/nchs/fastats/obesity-overweight.htm
Neill, A. M., Angus, S. M., Sajkov, D., & Mcevoy, R. D. (1997). Effects of sleep posture on upper airway stability in patients with obstructive sleep apnea. American Journal of Respiratory and Critical Care Medicine, 155(1), 199–204. http://doi.org/10.1164/ajrccm.155.1.9001312
Loord, H., & Hultcrantz, E. (2007). Positioner–a method for preventing sleep apnea. Acta Oto-Laryngologica, 127(8), 861–868. http://doi.org/10.1080/00016480601089390
Szollosi, I., Roebuck, T., Thompson, B., & Naughton, M. T. (2006). Lateral Sleeping Position Reduces Severity of Central Sleep Apnea / Cheyne-Stokes Respiration. Sleep, 29(8), 1045–1051. http://doi.org/10.1093/sleep/29.8.1045
Silverberg DS, Iaina A, Oksenberg A. Treating obstructive sleep apnea improves essential hypertension and quality of life. Am Fam Physician. 2002;65(2):229-236. https://pubmed.ncbi.nlm.nih.gov/11820487/
Aurora, R. N., Chowdhuri, S., Ramar, K., Bista, S. R., Casey, K. R., Lamm, C. I., … Tracy, S. L. (2012). The Treatment of Central Sleep Apnea Syndromes in Adults: Practice Parameters with an Evidence-Based Literature Review and Meta-Analyses. Sleep, 35(1), 17–40. http://doi.org/10.5665/sleep.1580
Hsu, A. A. L., & Lo, C. (2003). Continuous positive airway pressure therapy in sleep apnoea. Respirology, 8(4), 447–454. http://doi.org/10.1046/j.1440-1843.2003.00494.x
Patel, S. R., White, D. P., Malhotra, A., Stanchina, M. L., & Ayas, N. T. (2003). Continuous Positive Airway Pressure Therapy for Treating gess in a Diverse Population With Obstructive Sleep Apnea. Archives of Internal Medicine, 163(5), 565. http://doi.org/10.1001/archinte.163.5.565
Sundaram, S., Lim, J., & Lasserson, T. J. (2005). Surgery for obstructive sleep apnoea in adults. Cochrane Database of Systematic Reviews. http://doi.org/10.1002/14651858.cd001004.pub2
Chen, H., & Lowe, A. A. (2012). Updates in oral appliance therapy for snoring and obstructive sleep apnea. Sleep and Breathing, 17(2), 473–486. http://doi.org/10.1007/s11325-012-0712-4
Gaisl, T., Haile, S. R., Thiel, S., Osswald, M., & Kohler, M. (2019). Efficacy of pharmacotherapy for OSA in adults: A systematic review and network meta-analysis. Sleep Medicine Reviews, 46, 74–86. http://doi.org/10.1016/j.smrv.2019.04.009
Ohayon, M., Wickwire, E. M., Hirshkowitz, M., Albert, S. M., Avidan, A., Daly, F. J., … Vitiello, M. V. (2017). National Sleep Foundations sleep quality recommendations: first report. Sleep Health, 3(1), 6–19. http://doi.org/10.1016/j.sleh.2016.11.006
Youngstedt, S. D., Goff, E. E., Reynolds, A. M., Kripke, D. F., Irwin, M. R., Bootzin, R. R., … Jean-Louis, G. (2016). Has adult sleep duration declined over the last 50 years? Sleep Medicine Reviews, 28, 69–85. http://doi.org/10.1016/j.smrv.2015.08.004
Chaput, J.-P., Mcneil, J., Després, J.-P., Bouchard, C., & Tremblay, A. (2013). Seven to Eight Hours of Sleep a Night Is Associated with a Lower Prevalence of the Metabolic Syndrome and Reduced Overall Cardiometabolic Risk in Adults. PLoS ONE, 8(9). http://doi.org/10.1371/journal.pone.0072832
Wild, C. J., Nichols, E. S., Battista, M. E., Stojanoski, B., & Owen, A. M. (2018). Dissociable effects of self-reported daily sleep duration on high-level cognitive abilities. Sleep, 41(12). http://doi.org/10.1093/sleep/zsy182
Hirshkowitz, M., Whiton, K., Albert, S. M., Alessi, C., Bruni, O., Doncarlos, L., … Hillard, P. J. A. (2015). National Sleep Foundation’s sleep time duration recommendations: methodology and results summary. Sleep Health, 1(1), 40–43. http://doi.org/10.1016/j.sleh.2014.12.010
Cappuccio, F. P., Delia, L., Strazzullo, P., & Miller, M. A. (2010). Sleep Duration and All-Cause Mortality: A Systematic Review and Meta-Analysis of Prospective Studies. Sleep, 33(5), 585–592. http://doi.org/10.1093/sleep/33.5.585
Gottlieb, D. J., Punjabi, N. M., Newman, A. B., Resnick, H. E., Redline, S., Baldwin, C. M., & Nieto, F. J. (2005). Association of Sleep Time With Diabetes Mellitus and Impaired Glucose Tolerance. Archives of Internal Medicine, 165(8), 863. http://doi.org/10.1001/archinte.165.8.863
Short, M. A., Agostini, A., Lushington, K., & Dorrian, J. (2015). A systematic review of the sleep, sleepiness, and performance implications of limited wake shift work schedules. Scandinavian Journal of Work, Environment & Health, 41(5), 425–440. http://doi.org/10.5271/sjweh.3509
Cappuccio, F. P., Taggart, F. M., Kandala, N.-B., Currie, A., Peile, E., Stranges, S., & Miller, M. A. (2008). Meta-Analysis of Short Sleep Duration and Obesity in Children and Adults. Sleep, 31(5), 619–626. http://doi.org/10.1093/sleep/31.5.619
Mong, J. A., & Cusmano, D. M. (2016). Sex differences in sleep: impact of biological sex and sex steroids. Philosophical Transactions of the Royal Society B: Biological Sciences, 371(1688), 20150110. http://doi.org/10.1098/rstb.2015.0110
Krishnan, V., & Collop, N. A. (2006). Gender differences in sleep disorders. Current Opinion in Pulmonary Medicine, 12(6), 383–389. http://doi.org/10.1097/01.mcp.0000245705.69440.6a
Mehta, N., Shafi, F., & Bhat, A. (2015). Unique Aspects of Sleep in Women. Missouri medicine, 112(6), 430–434. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168103/
Moline, M. L., Broch, L., & Zak, R. (2004). Sleep in women across the life cycle from adulthood through menopause. Medical Clinics of North America, 88(3), 705–736. http://doi.org/10.1016/j.mcna.2004.01.009
He, Y., Jones, C. R., Fujiki, N., Xu, Y., Guo, B., Holder, J. L., … Fu, Y.-H. (2009). The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals. Science, 325(5942), 866–870. http://doi.org/10.1126/science.1174443
Theorell-Haglöw, J., Berglund, L., Berne, C., & Lindberg, E. (2014). Both habitual short sleepers and long sleepers are at greater risk of obesity: a population-based 10-year follow-up in women. Sleep Medicine, 15(10), 1204–1211. http://doi.org/10.1016/j.sleep.2014.02.014
Mezick, E. J., Wing, R. R., & Mccaffery, J. M. (2014). Associations of self-reported and actigraphy-assessed sleep characteristics with body mass index and waist circumference in adults: moderation by gender. Sleep Medicine, 15(1), 64–70. http://doi.org/10.1016/j.sleep.2013.08.784
Kim, S. J. (2011). Relationship Between Weekend Catch-up Sleep and Poor Performance on Attention Tasks in Korean Adolescents. Archives of Pediatrics & Adolescent Medicine, 165(9), 806. http://doi.org/10.1001/archpediatrics.2011.128
Kim, C.-W., Choi, M.-K., Im, H.-J., Kim, O.-H., Lee, H.-J., Song, J., … Park, K.-H. (2012). Weekend catch-up sleep is associated with decreased risk of being overweight among fifth-grade students with short sleep duration. Journal of Sleep Research, 21(5), 546–551. http://doi.org/10.1111/j.1365-2869.2012.01013.x
Sun, W., Ling, J., Zhu, X., Lee, T. M.-C., & Li, S. X. (2019). Associations of weekday-to-weekend sleep differences with academic performance and health-related outcomes in school-age children and youths. Sleep Medicine Reviews, 46, 27–53. http://doi.org/10.1016/j.smrv.2019.04.003
Kang, S.-G., Lee, Y. J., Kim, S. J., Lim, W., Lee, H.-J., Park, Y.-M., … Hong, J. P. (2014). Weekend catch-up sleep is independently associated with suicide attempts and self-injury in Korean adolescents. Comprehensive Psychiatry, 55(2), 319–325. http://doi.org/10.1016/j.comppsych.2013.08.023
Zhao, M., Tuo, H., Wang, S., & Zhao, L. (2020). The Effects of Dietary Nutrition on Sleep and Sleep Disorders. Mediators of Inflammation, 2020, 1–7. http://doi.org/10.1155/2020/3142874
Doherty, Madigan, Warrington, & Ellis. (2019). Sleep and Nutrition Interactions: Implications for Athletes. Nutrients, 11(4), 822. http://doi.org/10.3390/nu11040822
Sutanto CN, Wang MX, Tan D, Kim JE. Association of Sleep Quality and Macronutrient Distribution: A Systematic Review and Meta-Regression. Nutrients. 2020 Jan 2;12(1):126. doi: 10.3390/nu12010126. PMID: 31906452; PMCID: PMC7019667. https://pubmed.ncbi.nlm.nih.gov/31906452/
Peuhkuri, K., Sihvola, N., & Korpela, R. (2012). Diet promotes sleep duration and quality. Nutrition Research, 32(5), 309–319. http://doi.org/10.1016/j.nutres.2012.03.009
Afaghi, A., Oconnor, H., & Chow, C. M. (2007). High-glycemic-index carbohydrate meals shorten sleep onset. The American Journal of Clinical Nutrition, 85(2), 426–430. http://doi.org/10.1093/ajcn/85.2.426
Golem, D. L., Martin-Biggers, J. T., Koenings, M. M., Davis, K. F., & Byrd-Bredbenner, C. (2014). An Integrative Review of Sleep for Nutrition Professionals. Advances in Nutrition, 5(6), 742–759. http://doi.org/10.3945/an.114.006809
Grandner, M. A., Jackson, N., Gerstner, J. R., & Knutson, K. L. (2013). Sleep symptoms associated with intake of specific dietary nutrients. Journal of Sleep Research, 23(1), 22–34. http://doi.org/10.1111/jsr.12084
Porter, J., & Horne, J. (1981). Bed-time food supplements and sleep: Effects of different carbohydrate levels. Electroencephalography and Clinical Neurophysiology, 51(4), 426–433. http://doi.org/10.1016/0013-4694(81)90106-1
Halson, S. L. (2014). Sleep in Elite Athletes and Nutritional Interventions to Enhance Sleep. Sports Medicine, 44(S1), 13–23. http://doi.org/10.1007/s40279-014-0147-0
Rondanelli, M., Opizzi, A., Monteferrario, F., Antoniello, N., Manni, R., & Klersy, C. (2011). The Effect of Melatonin, Magnesium, and Zinc on Primary Insomnia in Long-Term Care Facility Residents in Italy: A Double-Blind, Placebo-Controlled Clinical Trial. Journal of the American Geriatrics Society, 59(1), 82–90. http://doi.org/10.1111/j.1532-5415.2010.03232.x
Tahara, Y., & Shibata, S. (2014). Chrono-biology, Chrono-pharmacology, and Chrono-nutrition. Journal of Pharmacological Sciences, 124(3), 320–335. http://doi.org/10.1254/jphs.13r06cr
Landolt, H.-P., Werth, E., Borbély, A. A., & Dijk, D.-J. (1995). Caffeine intake (200 mg) in the morning affects human sleep and EEG power spectra at night. Brain Research, 675(1-2), 67–74. http://doi.org/10.1016/0006-8993(95)00040-w
Gottesmann, C. (2002). GABA mechanisms and sleep. Neuroscience, 111(2), 231–239. http://doi.org/10.1016/s0306-4522(02)00034-9
Campbell, S. S., Dawson, D., & Anderson, M. W. (1993). Alleviation of Sleep Maintenance Insomnia with Timed Exposure to Bright Light. Journal of the American Geriatrics Society, 41(8), 829–836. http://doi.org/10.1111/j.1532-5415.1993.tb06179.x
Zhao, J., Tian, Y., Nie, J., Xu, J., & Liu, D. (2012). Red Light and the Sleep Quality and Endurance Performance of Chinese Female Basketball Players. Journal of Athletic Training, 47(6), 673–678. http://doi.org/10.4085/1062-6050-47.6.08
Smolensky, M. H., Sackett-Lundeen, L. L., & Portaluppi, F. (2015). Nocturnal light pollution and underexposure to daytime sunlight: Complementary mechanisms of circadian disruption and related diseases. Chronobiology International, 32(8), 1029–1048. http://doi.org/10.3109/07420528.2015.1072002
Düzgün, G., & Akyol, A. D. (2017). Effect of Natural Sunlight on Sleep Problems and Sleep Quality of the Elderly Staying in the Nursing Home. Holistic Nursing Practice, 31(5), 295–302. http://doi.org/10.1097/hnp.0000000000000206
Valham, F., Sahlin, C., Stenlund, H., & Franklin, K. A. (2012). Ambient Temperature and Obstructive Sleep Apnea: Effects on Sleep, Sleep Apnea, and Morning Alertness. Sleep, 35(4), 513–517. http://doi.org/10.5665/sleep.1736
Okamoto-Mizuno, K., Tsuzuki, K., & Mizuno, K. (2004). Effects of mild heat exposure on sleep stages and body temperature in older men. International Journal of Biometeorology, 49(1). http://doi.org/10.1007/s00484-004-0209-3
St-Onge, M.-P., & Shechter, A. (2014). Sleep disturbances, body fat distribution, food intake and/or energy expenditure: pathophysiological aspects. Hormone Molecular Biology and Clinical Investigation, 17(1). http://doi.org/10.1515/hmbci-2013-0066
Chaput, J.-P., Després, J.-P., Bouchard, C., & Tremblay, A. (2008). The Association Between Sleep Duration and Weight Gain in Adults: A 6-Year Prospective Study from the Quebec Family Study. Sleep, 31(4), 517–523. http://doi.org/10.1093/sleep/31.4.517
Dekker, S. A., Noordam, R., Biermasz, N. R., Roos, A., Lamb, H. J., Rosendaal, F. R., … Mutsert, R. (2018). Habitual Sleep Measures are Associated with Overall Body Fat, and not Specifically with Visceral Fat, in Men and Women. Obesity, 26(10), 1651–1658. http://doi.org/10.1002/oby.22289
Tunnicliffe, J. M., Erdman, K. A., Reimer, R. A., Lun, V., & Shearer, J. (2008). Consumption of dietary caffeine and coffee in physically active populations: physiological interactions. Applied Physiology, Nutrition, and Metabolism, 33(6), 1301–1310. http://doi.org/10.1139/h08-124
Mahoney, C. R., Giles, G. E., Marriott, B. P., Judelson, D. A., Glickman, E. L., Geiselman, P. J., & Lieberman, H. R. (2019). Intake of caffeine from all sources and reasons for use by college students. Clinical Nutrition, 38(2), 668–675. http://doi.org/10.1016/j.clnu.2018.04.004
Binks, H., Vincent, G. E., Gupta, C., Irwin, C., & Khalesi, S. (2020). Effects of Diet on Sleep: A Narrative Review. Nutrients, 12(4), 936. http://doi.org/10.3390/nu12040936
Rao, T. P., Ozeki, M., & Juneja, L. R. (2015). In Search of a Safe Natural Sleep Aid. Journal of the American College of Nutrition, 34(5), 436–447. http://doi.org/10.1080/07315724.2014.926153
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012 Dec;17(12):1161-9. https://pubmed.ncbi.nlm.nih.gov/23853635/
Aspy, D. J., Madden, N. A., & Delfabbro, P. (2018). Effects of Vitamin B6 (Pyridoxine) and a B Complex Preparation on Dreaming and Sleep. Perceptual and Motor Skills, 003151251877032. http://doi.org/10.1177/0031512518770326
Parazzini F. Resveratrol, tryptophanum, glycine and vitamin E: a nutraceutical approach to sleep disturbance and irritability in peri- and post-menopause. Minerva Ginecol. 2015;67(1):1-5. https://pubmed.ncbi.nlm.nih.gov/25660429/
Siegel JM. The neurotransmitters of sleep. J Clin Psychiatry. 2004;65 Suppl 16:4-7. https://pubmed.ncbi.nlm.nih.gov/15575797/
Djeridane, Y., Touitou, Y. Chronic diazepam administration differentially affects melatonin synthesis in rat pineal and Harderian glands. Psychopharmacology154, 403–407 (2001). https://doi.org/10.1007/s002130000631
Betti L, Palego L, Demontis GC, Miraglia F, Giannaccini G. Hydroxyindole-O-methyltransferase (HIOMT) activity in the retina of melatonin-proficient mice. Heliyon. 2019;5(9):e02417. Published 2019 Sep 14. doi:10.1016/j.heliyon.2019.e02417
Haduch, A., Bromek, E., Wójcikowski, J., Gołembiowska, K., Daniel, W.. Melatonin Supports Serotonin Formation by Brain CYP2D. Drug Metabolism and DispositionMarch 1, 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
Morton, D. J. (1987). Mechanism of Inhibition of Bovine Pineal Gland Hydroxyindole-O-Methyltransferase (EC 2.1.1.4) by Divalent Cations. Journal of Pineal Research, 4(3), 295–303. http://doi.org/10.1111/j.1600-079x.1987.tb00867.x
Markova-Car, E. P., Jurišić, D., Ilić, N., & Pavelić, S. K. (2014). Running for time: circadian rhythms and melanoma. Tumor Biology, 35(9), 8359–8368. http://doi.org/10.1007/s13277-014-1904-2
Slominski AT, Zmijewski MA, Skobowiat C, Zbytek B, Slominski RM, Steketee JD. Sensing the environment: regulation of local and global homeostasis by the skin’s neuroendocrine system. Adv Anat Embryol Cell Biol. 2012;212:v-115. doi:10.1007/978-3-642-19683-6_1 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422784/
Chalupsky, K., Kračun, D., Kanchev, I., Bertram, K., & Görlach, A. (2015). Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase. Antioxidants & Redox Signaling, 23(14), 1076–1091. http://doi.org/10.1089/ars.2015.6329
Dianzani, I., Sanctis, L. D., Smooker, P. M., Gough, T. J., Alliaudi, C., Brusco, A., … Cotton, R. G. H. (1998). Dihydropteridine reductase deficiency: Physical structure of the QDPR gene, identification of two new mutations and genotype–phenotype correlations. Human Mutation, 12(4), 267–273. http://doi.org/10.1002/(sici)1098-1004(1998)12:4<267::aid-humu8>3.0.co;2-c
Nichol, C. A., Lee, C. L., Edelstein, M. P., Chao, J. Y., & Duch, D. S. (1983). Biosynthesis of tetrahydrobiopterin by de novo and salvage pathways in adrenal medulla extracts, mammalian cell cultures, and rat brain in vivo. Proceedings of the National Academy of Sciences, 80(6), 1546–1550. http://doi.org/10.1073/pnas.80.6.1546
Titus, F., Dávalos, A., Alom, J., & Codina, A. (1986). 5-Hydroxytryptophan versus Methysergide in the Prophylaxis of Migraine. European Neurology, 25(5), 327–329. http://doi.org/10.1159/000116030
Birdsall TC. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev. 1998;3(4):271-280. https://pubmed.ncbi.nlm.nih.gov/9727088/
Volpi-Abadie J, Kaye AM, Kaye AD. Serotonin syndrome. Ochsner J. 2013;13(4):533-540. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865832/
Valadas, J. S., Esposito, G., Vandekerkhove, D., Miskiewicz, K., Deaulmerie, L., Raitano, S., … Verstreken, P. (2018). ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson’s Disease. Neuron, 98(6). http://doi.org/10.1016/j.neuron.2018.05.022
Chung SY, Moriyama T, Uezu E, et al. Administration of phosphatidylcholine increases brain acetylcholine concentration and improves memory in mice with dementia. J Nutr. 1995;125(6):1484-1489. doi:10.1093/jn/125.6.1484 https://pubmed.ncbi.nlm.nih.gov/7782901/
Montgomery, P., Burton, J. R., Sewell, R. P., Spreckelsen, T. F., & Richardson, A. J. (2014). Fatty acids and sleep in UK children: subjective and pilot objective sleep results from the DOLAB study – a randomized controlled trial. Journal of Sleep Research, 23(4), 364–388. http://doi.org/10.1111/jsr.12135
Alzoubi, K. H., Mayyas, F., & Zamzam, H. I. A. (2019). Omega-3 fatty acids protects against chronic sleep-deprivation induced memory impairment. Life Sciences, 227, 1–7. http://doi.org/10.1016/j.lfs.2019.04.028
Nasehi, M., Mosavi-Nezhad, S.-M., Khakpai, F., & Zarrindast, M.-R. (2018). The role of omega-3 on modulation of cognitive deficiency induced by REM sleep deprivation in rats. Behavioural Brain Research, 351, 152–160. http://doi.org/10.1016/j.bbr.2018.06.002
Jahangard, L., Sadeghi, A., Ahmadpanah, M., Holsboer-Trachsler, E., Bahmani, D. S., Haghighi, M., & Brand, S. (2018). Influence of adjuvant omega-3-polyunsaturated fatty acids on depression, sleep, and emotion regulation among outpatients with major depressive disorders – Results from a double-blind, randomized and placebo-controlled clinical trial. Journal of Psychiatric Research, 107, 48–56. http://doi.org/10.1016/j.jpsychires.2018.09.016
Scorza, F. A., Cavalheiro, E. A., Scorza, C. A., Galduróz, J. C. F., Tufik, S., & Andersen, M. L. (2013). Sleep Apnea and Inflammation – Getting a Good Night’s Sleep with Omega-3 Supplementation. Frontiers in Neurology, 4. http://doi.org/10.3389/fneur.2013.00193
Hansen, A. L., Dahl, L., Olson, G., Thornton, D., Graff, I. E., Frøyland, L., … Pallesen, S. (2014). Fish Consumption, Sleep, Daily Functioning, and Heart Rate Variability. Journal of Clinical Sleep Medicine, 10(05), 567–575. http://doi.org/10.5664/jcsm.3714
Xie, L., Kang, H., Xu, Q., Chen, M. J., Liao, Y., Thiyagarajan, M., … Nedergaard, M. (2013). Sleep Drives Metabolite Clearance from the Adult Brain. Science, 342(6156), 373–377. http://doi.org/10.1126/science.1241224
Varshavsky, A. (2012). Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis. Protein Science, 21(11), 1634–1661. http://doi.org/10.1002/pro.2148
Mackiewicz, M., Shockley, K. R., Romer, M. A., Galante, R. J., Zimmerman, J. E., Naidoo, N., … Pack, A. I. (2007). Macromolecule biosynthesis: a key function of sleep. Physiological Genomics, 31(3), 441–457. http://doi.org/10.1152/physiolgenomics.00275.2006
Scharf, M. T., Naidoo, N., Zimmerman, J. E., & Pack, A. I. (2008). The energy hypothesis of sleep revisited. Progress in Neurobiology, 86(3), 264–280. http://doi.org/10.1016/j.pneurobio.2008.08.003
Horne, J. (2009). REM sleep, energy balance and ‘optimal foraging.’ Neuroscience & Biobehavioral Reviews, 33(3), 466–474. http://doi.org/10.1016/j.neubiorev.2008.12.002
Berger, R. J., & Phillips, N. H. (1995). Energy conservation and sleep. Behavioural Brain Research, 69(1-2), 65–73. http://doi.org/10.1016/0166-4328(95)00002-b
Benington, J. H., & Heller, H. C. (1995). Restoration of brain energy metabolism as the function of sleep. Progress in Neurobiology, 45(4), 347–360. http://doi.org/10.1016/0301-0082(94)00057-o
Abel, T., Havekes, R., Saletin, J. M., & Walker, M. P. (2013). Sleep, Plasticity and Memory from Molecules to Whole-Brain Networks. Current Biology, 23(17). http://doi.org/10.1016/j.cub.2013.07.025
Rasch, B., & Born, J. (2013). About Sleeps Role in Memory. Physiological Reviews, 93(2), 681–766. http://doi.org/10.1152/physrev.00032.2012
Cirelli, C., & Tononi, G. (2008). Is Sleep Essential? PLoS Biology, 6(8). http://doi.org/10.1371/journal.pbio.0060216
Siegel, J. M. (2005). Clues to the functions of mammalian sleep. Nature, 437(7063), 1264–1271. http://doi.org/10.1038/nature04285
Campbell, S. S., & Tobler, I. (1984). Animal sleep: A review of sleep duration across phylogeny. Neuroscience & Biobehavioral Reviews, 8(3), 269–300. http://doi.org/10.1016/0149-7634(84)90054-x
Tobler, I. (1995). Is sleep fundamentally different between mammalian species? Behavioural Brain Research, 69(1-2), 35–41. http://doi.org/10.1016/0166-4328(95)00025-o
Tononi, G., & Cirelli, C. (2006). Sleep function and synaptic homeostasis. Sleep Medicine Reviews, 10(1), 49–62. http://doi.org/10.1016/j.smrv.2005.05.002
Dongen, H. P. A. V., Vitellaro, K. M., & Dinges, D. F. (2005). Individual Differences in Adult Human Sleep and Wakefulness: Leitmotif for a Research Agenda. Sleep, 28(4), 479–498. http://doi.org/10.1093/sleep/28.4.479
Vyazovskiy, V. V., & Delogu, A. (2014). NREM and REM Sleep. The Neuroscientist, 20(3), 203–219. http://doi.org/10.1177/1073858413518152
Mignot, E. (2008). Why We Sleep: The Temporal Organization of Recovery. PLoS Biology, 6(4). http://doi.org/10.1371/journal.pbio.0060106
Siegel, J. M. (2009). Sleep viewed as a state of adaptive inactivity. Nature Reviews Neuroscience, 10(10), 747–753. http://doi.org/10.1038/nrn2697
Horne, J. (2000). REM sleep — by default? Neuroscience & Biobehavioral Reviews, 24(8), 777–797. http://doi.org/10.1016/s0149-7634(00)00037-3
Baran, B., Pace-Schott, E. F., Ericson, C., & Spencer, R. M. C. (2012). Processing of Emotional Reactivity and Emotional Memory over Sleep. Journal of Neuroscience, 32(3), 1035–1042. http://doi.org/10.1523/jneurosci.2532-11.2012
Tononi, G., & Cirelli, C. (2014). Sleep and the Price of Plasticity: From Synaptic and Cellular Homeostasis to Memory Consolidation and Integration. Neuron, 81(1), 12–34. http://doi.org/10.1016/j.neuron.2013.12.025
Li, J., Vitiello, M. V., & Gooneratne, N. S. (2018). Sleep in Normal Aging. Sleep Medicine Clinics, 13(1), 1–11. http://doi.org/10.1016/j.jsmc.2017.09.001
Murillo-Rodriguez, E., Arias-Carrion, O., Zavala-Garcia, A., Sarro-Ramirez, A., & Huitron-Resendiz, S. (2012). Basic Sleep Mechanisms: An Integrative Review. Central Nervous System Agents in Medicinal Chemistry, 12(1), 38–54. http://doi.org/10.2174/187152412800229107
Weber, F. D. (2018). Sleep: Eye-Opener Highlights Sleep’s Organization. Current Biology, 28(5). http://doi.org/10.1016/j.cub.2018.01.054
Yetton, B. D., Mcdevitt, E. A., Cellini, N., Shelton, C., & Mednick, S. C. (2018). Quantifying sleep architecture dynamics and individual differences using big data and Bayesian networks. Plos One, 13(4). http://doi.org/10.1371/journal.pone.0194604
Colrain, I. M., Nicholas, C. L., & Baker, F. C. (2014). Alcohol and the sleeping brain. Handbook of Clinical Neurology Alcohol and the Nervous System, 415–431. http://doi.org/10.1016/b978-0-444-62619-6.00024-0
Zisapel, N. (2018). New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation. British Journal of Pharmacology, 175(16), 3190–3199. http://doi.org/10.1111/bph.14116
Tosini, G., Baba, K., Hwang, C. K., & Iuvone, P. M. (2012). Melatonin: An underappreciated player in retinal physiology and pathophysiology. Experimental Eye Research, 103, 82–89. http://doi.org/10.1016/j.exer.2012.08.009
Blasiak, J., Reiter, R. J., & Kaarniranta, K. (2016). Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration. Oxidative Medicine and Cellular Longevity, 2016, 1–12. http://doi.org/10.1155/2016/6819736
Bellingham, J., Chaurasia, S. S., Melyan, Z., Liu, C., Cameron, M. A., Tarttelin, E. E., … Lucas, R. J. (2006). Evolution of Melanopsin Photoreceptors: Discovery and Characterization of a New Melanopsin in Nonmammalian Vertebrates. PLoS Biology, 4(8). http://doi.org/10.1371/journal.pbio.0040254
Zaidi, F. H., Hull, J. T., Peirson, S. N., Wulff, K., Aeschbach, D., Gooley, J. J., … Lockley, S. W. (2007). Short-Wavelength Light Sensitivity of Circadian, Pupillary, and Visual Awareness in Humans Lacking an Outer Retina. Current Biology, 17(24), 2122–2128. http://doi.org/10.1016/j.cub.2007.11.034
Legates, T. A., Altimus, C. M., Wang, H., Lee, H.-K., Yang, S., Zhao, H., … Hattar, S. (2012). Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature, 491(7425), 594–598. http://doi.org/10.1038/nature11673
Sikka, G., Hussmann, G. P., Pandey, D., Cao, S., Hori, D., Park, J. T., … Berkowitz, D. E. (2014). Melanopsin mediates light-dependent relaxation in blood vessels. Proceedings of the National Academy of Sciences, 111(50), 17977–17982. http://doi.org/10.1073/pnas.1420258111
Buhr, E. D., Yoo, S.-H., & Takahashi, J. S. (2010). Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators. Science, 330(6002), 379–385. http://doi.org/10.1126/science.1195262
Robbins, R., Grandner, M. A., Buxton, O. M., Hale, L., Buysse, D. J., Knutson, K. L., … Jean-Louis, G. (2019). Sleep myths: an expert-led study to identify false beliefs about sleep that impinge upon population sleep health practices. Sleep Health, 5(4), 409–417. http://doi.org/10.1016/j.sleh.2019.02.002
Damiola, F. (2000). Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes & Development, 14(23), 2950–2961. http://doi.org/10.1101/gad.183500
Abel, T., Havekes, R., Saletin, J. M., & Walker, M. P. (2013). Sleep, Plasticity and Memory from Molecules to Whole-Brain Networks. Current Biology, 23(17). http://doi.org/10.1016/j.cub.2013.07.025
Muzet, A., Ehrhart, J., Candas, V., Libert, J. P., & Vogt, J. J. (1983). Rem Sleep and Ambient Temperature in Man. International Journal of Neuroscience, 18(1-2), 117–125. http://doi.org/10.3109/00207458308985885
Saini, C., Morf, J., Stratmann, M., Gos, P., & Schibler, U. (2012). Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators. Genes & Development, 26(6), 567–580. http://doi.org/10.1101/gad.183251.111
Franco P, Szliwowski H, Dramaix M, Kahn A. Influence of ambient temperature on sleep characteristics and autonomic nervous control in healthy infants. Sleep. 2000 May 1;23(3):401-7. https://pubmed.ncbi.nlm.nih.gov/10811384/
Libert JP, Candas V, Muzet A, Ehrhart J. Thermoregulatory adjustments to thermal transients during slow wave sleep and REM sleep in man. J Physiol (Paris). 1982;78(3):251-7 https://pubmed.ncbi.nlm.nih.gov/7166740/
Palca, J. W., Walker, J. M., & Berger, R. J. (1986). Thermoregulation, metabolism, and stages of sleep in cold-exposed men. Journal of Applied Physiology, 61(3), 940–947. http://doi.org/10.1152/jappl.1986.61.3.940
Lack. (2009). Chronotype differences in circadian rhythms of temperature, melatonin, and sleepiness as measured in a modified constant routine protocol. Nature and Science of Sleep, 1. http://doi.org/10.2147/nss.s6234
Samson, D. R., Crittenden, A. N., Mabulla, I. A., Mabulla, A. Z. P., & Nunn, C. L. (2017). Chronotype variation drives night-time sentinel-like behaviour in hunter–gatherers. Proceedings of the Royal Society B: Biological Sciences, 284(1858), 20170967. http://doi.org/10.1098/rspb.2017.0967
Walker, R. J., Kribs, Z. D., Christopher, A. N., Shewach, O. R., & Wieth, M. B. (2014). Age, the Big Five, and time-of-day preference: A mediational model. Personality and Individual Differences, 56, 170–174. http://doi.org/10.1016/j.paid.2013.09.003
Bjorness, T., & Greene, R. (2009). Adenosine and Sleep. Current Neuropharmacology, 7(3), 238–245. http://doi.org/10.2174/157015909789152182
Dworak, M., Diel, P., Voss, S., Hollmann, W., & Strüder, H. (2007). Intense exercise increases adenosine concentrations in rat brain: Implications for a homeostatic sleep drive. Neuroscience, 150(4), 789–795. http://doi.org/10.1016/j.neuroscience.2007.09.062
Rainnie, D., Grunze, H., Mccarley, R., & Greene, R. (1994). Adenosine inhibition of mesopontine cholinergic neurons: implications for EEG arousal. Science, 263(5147), 689–692. http://doi.org/10.1126/science.8303279
Daly, J. W., Shi, D., Nikodijevic, O., & Jacobson, K. A. (1994). The role of adenosine receptors in the central action of caffeine. Pharmacopsychoecologia, 7(2), 201–213. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373791/
